Protein Alignment HOXD4 and Scr

DIOPT Version :9

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 99/260 - (38%)
• Similarity: 121/260 - (46%)
• Gaps: 84/260 - (32%)

Human     8 VNSKYVDPKFPPCE------EYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSG 66
            ::::.:.||..|..      ..|..|.|         ||:..|.....||       .....|||
  Fly   210 LSTRDISPKLSPSSVVESVARSLNKGVL---------GGSLAAAAAAAGL-------NNNHSGSG 258

Human    67 PGPGSALPARGHGQEPGGPGG-----HYAAPGEPCPAPPAPPPAPLPGARAYSQSDP-----KQP 121
            ..              ||||.     |  :||               |..:.|:||.     ...
  Fly   259 VS--------------GGPGNVNVPMH--SPG---------------GGDSDSESDSGNEAGSSQ 292

Human   122 PSGTALKQPAVVYPWMKKVHV--NSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRR 184
            .||...|.|..:|||||:||:  ::||.|   ||.||.||:|||.|.||||||||||||||||||
  Fly   293 NSGNGKKNPPQIYPWMKRVHLGTSTVNAN---GETKRQRTSYTRYQTLELEKEFHFNRYLTRRRR 354

Human   185 IEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQPMAKDHH 249
            |||||.|||:|||||||||||||||||:||:               .|.::.| .|:.|....:|
  Fly   355 IEIAHALCLTERQIKIWFQNRRMKWKKEHKM---------------ASMNIVP-YHMGPYGHPYH 403

Human   250  249
              Fly   404  403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		21/105 (20%)
		Antp-type hexapeptide	133..138		3/4 (75%)
		Homeobox	157..210	CDD:306543	46/52 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		7/38 (18%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	47/52 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4116
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.960