Protein Alignment HOXD4 and bcd

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 203
• Identity: 59/203 - (29%)
• Similarity: 79/203 - (38%)
• Gaps: 42/203 - (20%)

Human    47 QPP---GLY--PRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAP 106
            |||   ..|  |.|.....|...|.|.|.|      |      |..|:..|....| |....|..
  Fly     3 QPPPDQNFYHHPLPHTHTHPHPHSHPHPHS------H------PHPHHQHPQLQLP-PQFRNPFD 54

Human   107 L-----PGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQV 166
            |     .||..|:...|..|   ..:.:|. |:|      ...:..:.....|:|:||.:|..|:
  Fly    55 LLFDERTGAINYNYIRPYLP---NQMPKPD-VFP------SEELPDSLVMRRPRRTRTTFTSSQI 109

Human   167 LELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWK---KDHK------LPNTKGRS 222
            .|||:.|...||||..|..:::..|.|...|:||||:|||.:.|   ..||      :|.:.|..
  Fly   110 AELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSYEGMPLSPGMK 174

Human   223 SSSSSSSS 230
            .|.....|
  Fly   175 QSDGDPPS 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		24/89 (27%)
		Antp-type hexapeptide	133..138		2/4 (50%)
		Homeodomain	155..211	CDD:459649	25/58 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		6/25 (24%)
bcd	NP_788587.1	Homeodomain	106..153	CDD:459649	20/46 (43%)