Protein Alignment HOXD4 and ind

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 220
• Identity: 73/220 - (33%)
• Similarity: 95/220 - (43%)
• Gaps: 53/220 - (24%)

Human    50 GLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYS 114
            |.||.|.....|.....|      |.......|...|.....||..|.:|.|...|.|.....:.
  Fly   127 GCYPSPPLSANPNSQQLP------PIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFD 185

Human   115 QSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNP------NYTGGEP--------------KRSRT 159
            :      |.|...|            |.:|.:|      |::.|.|              ||.||
  Fly   186 E------PQGKRFK------------HESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRT 232

Human   160 AYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSS 224
            |:|..|:||||:||..|.||:|.||||||:.|.|||:|:||||||||:|.|        ||.|.|
  Fly   233 AFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQK--------KGGSES 289

Human   225 SSSSSSCSSSVAP-SQHLQPMAKDH 248
            .:.:.|.:|:.:| :..:.|..|.|
  Fly   290 PTFNLSTNSNGSPQASPVSPQVKVH 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		18/76 (24%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeodomain	155..211	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		10/38 (26%)
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	38/63 (60%)