Protein Alignment Nna1 and Agtpbp1

DIOPT Version :10

• Sequence 1: NP_001285225.1
• Gene: Nna1 / 32329
• FlyBaseID: FBgn0265726
• Length: 1890
• Species: Drosophila melanogaster
• Sequence 2: NP_075817.2
• Gene: Agtpbp1 / 67269
• MGIID: 2159437
• Length: 1218
• Species: Mus musculus
• Alignment Length: 1214
• Identity: 307/1214 - (25%)
• Similarity: 459/1214 - (37%)
• Gaps: 417/1214 - (34%)

  Fly     5 VKDKENRNSAMGPEICEV--------QQHPSKQNDGFLGSFLSKGLK--TN-------------- 45
            :|.|.|...|:.....:|        .:|.::..:..:...:.:.||  ||
Mouse   231 LKSKTNARRAVDRGYVQVLLTIYVDWHRHDNRHRNMLIRKGILQSLKSVTNIKLGRKAFIDANGM 295

  Fly    46 QLVVNTDE-----KTLRPVARLKE-------PRDLFALPKDKDNDCSQQAPRWPVECQVIEERII 98
            :::.||.:     :||.|:.....       |::...||..|.:...|
Mouse   296 KILYNTSQECLAVRTLDPLVNTSSLIMRKCFPKNRLPLPTIKSSFHFQ----------------- 343

  Fly    99 HIPYVPAVPEPLNAPTGNELKPRPVGEENGIVVFSYSPISAVNYEKPKAKKEDD---------ES 154
             :|.:|.        ||      ||.:     ::|..|  .|:....::...||         |:
Mouse   344 -LPIIPV--------TG------PVAQ-----LYSLPP--EVDDVVDESDDNDDIDLEVENELEN 386

  Fly   155 SDESDYSSDSRQDSTPPSRSTPMRLAGGGECAPGKLNSVSKMINNVDNRSTSASLDDNDDY---- 215
            .|:.|.|..:....|..::..|.::       ||:.....||..::    ....:||..||
Mouse   387 EDDLDQSFKNDDIETDINKLRPQQV-------PGRTIEELKMYEHL----FPELVDDFQDYELIS 440

  Fly   216 -------YDDE------YDTSGGYC-GGSGEAKEKAIIKDLIEAKKKRYQEEAEVTPVGGGTARN 266
                   ::.:      ..|:|... |.||..|:..::|:....|    .|||:..|.|......
Mouse   441 KEPKPFVFEGKARGPIVVPTAGEEVPGNSGSVKKGVVMKERASPK----GEEAKEDPKGHDRTLP 501

  Fly   267 SRAASRSEASKDASDIDDIWKNNTSEYKPASPRYVLSQFGKNVTKAVIDRIVDHEDLVPPSGSQK 331
            .:...:|..:..|                       ..|..::.|| :|||.          .|.
Mouse   502 QQLGGQSRVAPSA-----------------------HSFNNDLVKA-LDRIT----------LQN 532

  Fly   332 VSNQFAVG-------PVKLPKTNIARLEVAFERSACQDRSKSRLKKKMSSSRRRRESTSDEDSS- 388
            |.:|.|.|       ...||.|.::..:      ||...:|.             .||..|..:
Mouse   533 VPSQVASGLNAGMRKDFGLPLTVLSCTK------ACPHVAKC-------------GSTLFEGRTV 578

  Fly   389 ------SSSLGNEEDEEVDDSDSDAENTGSGIGLRRILGSYSARLAGGAEKCPCPGSGSVSDTET 447
                  .:.:..|:||:.:...|                         .|:.|   |...||..|
Mouse   579 HLGKLCCTGVETEDDEDTESHSS-------------------------TEQAP---SVEASDGPT 615

  Fly   448 LVGDESRSRLAGSNGLHQQDVVCSRNRQAQS--------------------RSPLRSVPHTHAAT 492
                           ||..|:.....:..:|                    :.|:...|:
Mouse   616 ---------------LHDPDLYIEIVKNTKSVPEYSEVAYPDYFGHIPPPFKEPILERPY----- 660

  Fly   493 VAAAAAALARGRNRDKDGCLGGKDEKNMGMGVGTTGTSSMGTRTSSPVRNNVFRLSKDQHILLNS 557
                      |..|.|                               :..::.||.....|:...
Mouse   661 ----------GVQRTK-------------------------------IAQDIERLIHQNDIIDRV 684

  Fly   558 MTSQETTGTLISSTSTNQTTTTTNSSQSFLCSDLPQAQFSRSAVGGARFMTNCHPMNPEEYDGLE 622
            :...:           |.|.||                                   |||.|.|:
Mouse   685 VYDLD-----------NPTYTT-----------------------------------PEEGDTLK 703

  Fly   623 FESRFESGNLAKAVQITPTYYELYLRPDLYTSRSKQWFYFRVRRTRRKMLYRFSIVNLVKSDSLY 687
            |.|:||||||.|.:||..:.|:|.|..|:.::...|||||.|...|..:.|||:|:|..||:|.:
Mouse   704 FNSKFESGNLRKVIQIRKSEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKSNSQF 768

  Fly   688 NDGMQPVMYSTLGAKEKSEGWRRCGDNICYYRNDDESASSSANEDDEDNSTYTLTFTIEFEHDDD 752
            |.||||:|||...|......|.|.|.:||||:| ..|.||.|....:..|.||:|||:.|.|.||
Mouse   769 NYGMQPLMYSVQEALNARPWWIRMGTDICYYKN-HFSRSSVAAGGQKGKSYYTITFTVNFPHKDD 832

  Fly   753 TVFFAHSYPYTYSDLQDYLMEIQ-RHPVKSKFCKLRLLCRTLAGNNVYYLTVTA-PSSNEE---- 811
            ..:||:.||||||.||.:|.::: .|..:..:.:..:||.||:||....:|:|| |.||..
Mouse   833 VCYFAYHYPYTYSTLQMHLQKLESAHNPQQIYFRKDVLCETLSGNICPLVTITAMPESNYYEHIC 897

  Fly   812 NMRRKKSIVVSARVHPSETPASWMMKGLMDFITGDTTVAKRLRHKFIFKLVPMLNPDGVIVGNTR 876
            ..|.:..|.:||||||.||.|||:|||.::::..::..|:.||..:|||:||||||||||.||.|
Mouse   898 QFRTRPYIFLSARVHPGETNASWVMKGTLEYLMSNSPTAQSLRESYIFKIVPMLNPDGVINGNHR 962

  Fly   877 NSLTGKDLNRQYRTVIRETYPSIWYTK------AMIRRLIEECGVAMYCDMHAHSRKHNIFIYGC 935
            .||:|:|||||:::...|.:|:|::.|      |.::||     ..:|||.|.||||.|:|:|||
Mouse   963 CSLSGEDLNRQWQSPNPELHPTIYHAKGLLQYLAAVKRL-----PLVYCDYHGHSRKKNVFMYGC 1022

  Fly   936 ENKRNPEKKLTEQVFPLMLHKNSAD---------------------RFSFESCKFKIQRSKEGTG 979
            ..|        |.|:  ..|.|||.                     .|...||.|.:::|||.|.
Mouse  1023 SIK--------ETVW--HTHDNSASCDIVEDMGYRTLPKILSHIAPAFCMSSCSFVVEKSKESTA 1077

  Fly   980 RIVVWM-LGITNSYTIEASFGGSSLGSRKGTHFNTQDYEHMGRAFCETLLDYCDENPNKILNLLK 1043
            |:|||. :|:..|||:|::..|...|..||....|::.|.||..||..||
Mouse  1078 RVVVWREIGVQRSYTMESTLCGCDQGRYKGLQIGTRELEEMGAKFCVGLL--------------- 1127

  Fly  1044 QQDRLRSKIIERLMREGSSADEPLNIPLSDYSSD--EGNCSSSS 1085
                       ||.|..||.:..|...|.|:.:|  |.:|..:|
Mouse  1128 -----------RLKRLTSSLEYNLPSNLLDFENDLIESSCKVTS 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nna1	NP_001285225.1	Pepdidase_M14_N	623..758	CDD:407865	62/134 (46%)
		M14_AGBL2-3_like	780..1031	CDD:349478	111/283 (39%)
Agtpbp1	NP_075817.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..512		8/39 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	590..617		10/69 (14%)
		Pepdidase_M14_N	704..838	CDD:407865	62/134 (46%)
		M14_Nna1	861..1131	CDD:349477	113/310 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1193..1218