Protein Alignment Nna1 and Agbl1

DIOPT Version :10

• Sequence 1: NP_001285225.1
• Gene: Nna1 / 32329
• FlyBaseID: FBgn0265726
• Length: 1890
• Species: Drosophila melanogaster
• Sequence 2: NP_001419181.1
• Gene: Agbl1 / 308724
• RGDID: 1560280
• Length: 1125
• Species: Rattus norvegicus
• Alignment Length: 918
• Identity: 265/918 - (28%)
• Similarity: 400/918 - (43%)
• Gaps: 189/918 - (20%)

  Fly   329 SQKVSNQFAVGPVKLPKTNIARLEVAFERSACQDRSKSRLKKKMSSS---------------RRR 378
            :|.:...|::....|...|:..:..|..:...|....|||....:||               |..
  Rat   234 AQGMETLFSIAQTCLENKNMELVISAVIQILRQCYPVSRLPLATASSAYTFPAPGSTSLELVRHL 298

  Fly   379 RESTSDEDSSSSSLGNEE---DEEV------DDSDSDAENTGSGIGL---RRILGSYSARLAGGA 431
            .|...|:|      |:||   |.:|      ||.::|.....|..||   ...|..|.||
  Rat   299 TEEDFDDD------GDEEMDKDSDVEAGKEDDDLETDMSKLSSKPGLDLPEEELAQYDAR----- 352

  Fly   432 EKCPCPG-SGSVSDTETLVGDESRSR-LAGSNGLHQQDVVCSR----NRQAQS-RSPLRSVPHTH 489
                ||. |.|..:.|...||....| ...:|..|.......|    ||:.:| |.......||.
  Rat   353 ----CPELSCSFEELEPKCGDNLNFRDTLHANHHHIPSAASLRQHCCNREHRSWRQEGEDTVHTS 413

  Fly   490 AATVAAAAAALARGRNRDKDGCLGGKDEKNMGMGVGTTGTSSMGTRTSSPVRNNVFRLSKDQHIL 554
            ...:|....:..|..::.:......:..:..|:|:|::|..::..:|  |:....:.
  Rat   414 ILHMAKPGKSSVRSSSKQRSATNVNQSIQQNGLGIGSSGRGTLDIQT--PLEQAAWD-------- 468

  Fly   555 LNSMTSQETTGTLISSTSTNQTTTTTNSSQSFLCSDLPQAQF------------SRSAVGGAR-- 605
            :.:::....|.:..:||...:   :..:::..|........|            :|||||...
  Rat   469 IEAISCPRITASFSNSTKPEE---SHEAAEKLLHKHPKHIPFHDPHLYMANVMRTRSAVGFKTMA 530

  Fly   606 ---FMTNCHP-------------------------MNPEEY-------------------DGLEF 623
               |..:|.|                         :.|.:.                   |.|.|
  Rat   531 FPDFWGHCPPPTAQPLLDRKLGVQRIKILEDVRRLLQPSDVINKVVFSLDEPWPLQGSISDCLRF 595

  Fly   624 ESRFESGNLAKAVQITPTYYELYLRPDLYTSRSKQWFYFRVRRTRRKMLYRFSIVNLVKSDSLYN 688
            .|:||||||.||:|:....|:|.:..|:.:|:.:|||||:|...|..:.|||:|:|..|.:|.:|
  Rat   596 HSKFESGNLRKAIQVREFEYDLLVNADVNSSQHQQWFYFKVSGMRAAVPYRFNIINCEKPNSQFN 660

  Fly   689 DGMQPVMYSTLGAKEKSEGWRRCGDNICYYRNDDESASSSANEDDEDNSTYTLTFTIEFEHDDDT 753
            .||||.:||...|......|.|.|..||||:|.... :::|.:.......|||||.:.|.|::|.
  Rat   661 YGMQPTLYSVKEALLGRHAWIRTGSEICYYKNHYRQ-NAAAMDGASGKRYYTLTFAVTFPHNEDA 724

  Fly   754 VFFAHSYPYTYSDLQDYLMEIQRHPVKSKFCKLR--LLCRTLAGNNVYYLTVTA-PSSNE----E 811
            .:.|:.||||||.|..:| ||....:..:....|  :||:||.||....:|:|| |.||.    |
  Rat   725 CYLAYHYPYTYSTLMTHL-EILERSIDRREVYFRHDVLCQTLGGNPCPLVTITAFPESNSAEHLE 788

  Fly   812 NMRRKKSIVVSARVHPSETPASWMMKGLMDFITGDTTVAKRLRHKFIFKLVPMLNPDGVIVGNTR 876
            ..|.:...|::|||||.|:.|||:|||.::|:.....|||.||..|:||::|||||||||.||.|
  Rat   789 QFRCRPYQVITARVHPGESNASWVMKGTLEFLVSSDPVAKLLRENFVFKIIPMLNPDGVINGNHR 853

  Fly   877 NSLTGKDLNRQYRTVIRETYPSIWYTKAMIRRLIEE-CGVAMYCDMHAHSRKHNIFIYGCENKRN 940
            .||.|:|||||:........|:|::.|.:::.|... .|..::||.|.||:|.|:|:|||..|..
  Rat   854 CSLRGEDLNRQWLCPQVHLQPTIYHAKGLLQYLSSTGRGPVVFCDFHGHSQKKNVFLYGCSMKET 918

  Fly   941 --------PEKKLTEQV----FPLMLHKNSADRFSFESCKFKIQRSKEGTGRIVVWM-LGITNSY 992
                    ....|.|.|    .|.:|.| .|..|:..||.|.:::|:..|.|:|.|. :|::.||
  Rat   919 LWQAGCTVGGSALLEDVSYRTLPKILDK-LAPAFTMNSCSFLVEKSRASTARVVAWREMGVSRSY 982

  Fly   993 TIEASFGGSSLGSRKGTHFNTQDYEHMGRAFCETLLDYCDENPNKILN----------LLKQQDR 1047
            |:|:|:.|.:.|..:|..|.|::.|.||..:|..||         ||.          |.:....
  Rat   983 TMESSYCGCNQGPYQGLQFGTRELEEMGAMYCLGLL---------ILELKSASCSHKLLARASTL 1038

  Fly  1048 LRSKIIERLMREGSSA----------------DEPLNIPLSDYSSDEGNCSSSSDNEGKHSITTS 1096
            |.:.::|..::..||:                |||..:...||.:|     ||||:|  .:.|..
  Rat  1039 LNADVLEHYLQRCSSSSSSNSSNNNSRTSEVNDEPPCMEEIDYCAD-----SSSDSE--QNFTEL 1096

  Fly  1097 DLEGPCCA 1104
            |.:...||
  Rat  1097 DQQIQECA 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nna1	NP_001285225.1	Pepdidase_M14_N	623..758	CDD:407865	54/134 (40%)
		M14_AGBL2-3_like	780..1031	CDD:349478	107/271 (39%)
Agbl1	NP_001419181.1	Pepdidase_M14_N	595..729	CDD:407865	54/134 (40%)
		M14_Nna1	753..1018	CDD:349477	105/265 (40%)