Protein Alignment Nna1 and Agbl1

DIOPT Version :10

• Sequence 1: NP_001285225.1
• Gene: Nna1 / 32329
• FlyBaseID: FBgn0265726
• Length: 1890
• Species: Drosophila melanogaster
• Sequence 2: NP_001186153.1
• Gene: Agbl1 / 244071
• MGIID: 3646469
• Length: 1122
• Species: Mus musculus
• Alignment Length: 913
• Identity: 264/913 - (28%)
• Similarity: 400/913 - (43%)
• Gaps: 183/913 - (20%)

  Fly   329 SQKVSNQFAVGPVKLPKTNIARLEVAFERSACQDRSKSRLKKKMSSSR---RRRESTSDE---DS 387
            :|.:...|::....|...|:..:..|..:...|....|||....:||.   ....|||.|   :.
Mouse   234 AQGMETLFSIAQTCLENKNMELVISAVIQILRQCYPASRLPLVTASSAYTFPAPGSTSSELPLNL 298

  Fly   388 SSSSLGNEEDEEVDDSDSDAENTGSGIGLRRILGSYSAR---------LAGGAEKCP---CPGSG 440
            :.....::.|||: |.|||.|.......|...|...|::         ||.....||   |
Mouse   299 TEEDFDDDGDEEM-DKDSDVEAVKEDDDLETDLSKLSSKPGLDLPEEELAQYDAMCPELSC---- 358

  Fly   441 SVSDTETLVGDESRSRLAGSNGLHQQDVVCSRNRQAQSRSPLRS--VPHTHAA-------TVAAA 496
            |..:.|...||:          |:.:|.:.:.:....|.:.||.  ....|::       ||.::
Mouse   359 SFEELEPKCGDD----------LNNKDTLHANHHHIPSVASLRQHCFNREHSSWRQEREDTVHSS 413

  Fly   497 AAALARGRNRDKDGCLGGKDEKNMGMGVGTTGTSSMGTRTSSPVRNNVFRLSKDQHIL------- 554
            ...:.:          .||.      ||.::......|..:..::.|...:....|..
Mouse   414 ILHMVK----------TGKS------GVPSSSKQRSATNVNQSLQQNGLEIDSSGHDTSDIQAPL 462

  Fly   555 ------LNSMTSQETTGTLISSTSTNQTTTTTNSSQSFLCSDLP---------QAQFSRSAVGGA 604
                  :.:::....|.:..:||...::..............:|         .|..:|||||
Mouse   463 EQAAWDMEAISCPRITASFPNSTKPEESIGAAEKLLHTHAKHIPFHDPHLYIANAMRTRSAVG-- 525

  Fly   605 RFMT--------NC----------------------------HPMN-----------PEEYDG-- 620
             |.|        :|                            ||.:           |....|
Mouse   526 -FKTMAFPDLWGHCPPPAAQPMLDRKLGVQRIKILEDIRRLLHPSDVINKVVFSLDEPRPLQGSI 589

  Fly   621 ---LEFESRFESGNLAKAVQITPTYYELYLRPDLYTSRSKQWFYFRVRRTRRKMLYRFSIVNLVK 682
               |.|.|:||||||.||:|:....|:|.:..|:.:|:.:|||||:|...|..:.|.|:|:|..|
Mouse   590 SNCLMFHSKFESGNLRKAIQVREFEYDLLVNADVNSSQHQQWFYFKVSGMRAAVPYHFNIINCEK 654

  Fly   683 SDSLYNDGMQPVMYSTLGAKEKSEGWRRCGDNICYYRNDDESASSSANEDDE-DNSTYTLTFTIE 746
            .:|.:|.||||.:||...|......|.|.|.:||||:|  ....::|..|.. ....|||||.:.
Mouse   655 PNSQFNYGMQPTLYSVKEALLGRPAWIRTGSDICYYKN--HYRQNAATMDGALGKRYYTLTFAVT 717

  Fly   747 FEHDDDTVFFAHSYPYTYSDLQDYLMEIQR---HPVKSKFCKLRLLCRTLAGNNVYYLTVTA-PS 807
            |.|::|..:.|:.||||||.|..:|..::|   |  :..:.:..:||:||.||....:|:|| |.
Mouse   718 FPHNEDACYLAYHYPYTYSTLMTHLEILERSIDH--REIYFRHDVLCQTLGGNPCPLVTITAFPE 780

  Fly   808 SNE----ENMRRKKSIVVSARVHPSETPASWMMKGLMDFITGDTTVAKRLRHKFIFKLVPMLNPD 868
            ||.    |..|.:...|::|||||.|:.|||:|||.::|:.....|||.||..|:||::||||||
Mouse   781 SNSTEHLEQFRCRPYQVITARVHPGESNASWVMKGTLEFLVSSDPVAKLLRENFVFKIIPMLNPD 845

  Fly   869 GVIVGNTRNSLTGKDLNRQYRTVIRETYPSIWYTKAMIRRLIEE-CGVAMYCDMHAHSRKHNIFI 932
            |||.||.|.||.|:|||||:.:......|:|::.|.::..|... .|..::||.|.||:|.|:|:
Mouse   846 GVINGNHRCSLRGEDLNRQWLSPQAHLQPTIYHAKGLLHYLSSTGRGPVVFCDFHGHSQKKNVFL 910

  Fly   933 YGCENKRN--------PEKKLTEQV----FPLMLHKNSADRFSFESCKFKIQRSKEGTGRIVVWM 985
            |||..|..        .|..|.|.|    .|.:|.| .|..|:..||.|.:::|:..|.|:|||.
Mouse   911 YGCSMKETLWQAGCTVGESALLEDVSYRTLPKILDK-LAPAFTMNSCSFLVEKSRASTARVVVWR 974

  Fly   986 -LGITNSYTIEASFGGSSLGSRKGTHFNTQDYEHMGRAFCETLLDYCDENPNKILNLL-KQQDRL 1048
             :|::.|||:|:|:.|.:.|..:|..|.|.:.|.||..:|..||....::.|....|| :....|
Mouse   975 EMGVSRSYTMESSYCGCNQGPYQGLQFGTGELEEMGAMYCLGLLILELKSVNCSHKLLARASSLL 1039

  Fly  1049 RSKIIERLMREGSSA------------DEPLNIPLSDYSSDEGNCSSSSDNEGKHSITTSDLEGP 1101
            .:.::|..::..||:            |||..:...|||:|     ||||.|  .:.|..|.:..
Mouse  1040 NADVLEHYLQRCSSSSSNSSNRTSEVDDEPYCMEEIDYSAD-----SSSDAE--QNFTELDRQIQ 1097

  Fly  1102 CCA 1104
            .||
Mouse  1098 ECA 1100

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nna1	NP_001285225.1	Pepdidase_M14_N	623..758	CDD:407865	54/135 (40%)
		M14_AGBL2-3_like	780..1031	CDD:349478	108/269 (40%)
Agbl1	NP_001186153.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..338		15/51 (29%)
		Pepdidase_M14_N	595..729	CDD:407865	54/135 (40%)
		M14_Nna1	753..1018	CDD:349477	106/265 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1099..1122		2/2 (100%)