Protein Alignment Nna1 and Agbl5

DIOPT Version :10

• Sequence 1: NP_001285225.1
• Gene: Nna1 / 32329
• FlyBaseID: FBgn0265726
• Length: 1890
• Species: Drosophila melanogaster
• Sequence 2: XP_036020907.1
• Gene: Agbl5 / 231093
• MGIID: 2441745
• Length: 1007
• Species: Mus musculus
• Alignment Length: 1006
• Identity: 236/1006 - (23%)
• Similarity: 367/1006 - (36%)
• Gaps: 327/1006 - (32%)

  Fly   597 SRSAVGGARFMTNCHPMNPEEY--DGLEFESRFESGNLAKAVQI--------------------- 638
            |...:.|||   .|.|....|.  .||.|.|||:|||||...::
Mouse    77 SSQGLCGAR---GCFPSPTMELRCGGLLFSSRFDSGNLAHVEKVETVSSDGEGVGGVATAPASGS 138

  Fly   639 --TPTY-YELYLRPDL----YTSRSKQWFYFRVRRTRRKMLYRFSIVNLVKSDSLYNDGMQPVMY 696
              :|.| :.::.|||.    |.:.::.||||.||......|.:.:|:|:.|...||:.||.|.:
Mouse   139 AASPDYEFNVWTRPDCAETEYENGNRSWFYFSVRGGTPGKLIKINIMNMNKQSKLYSQGMAPFV- 202

  Fly   697 STLGAKEKSEGWRR--------CGDNI--CYYRNDDESASSSANEDDE----DNSTYTLTFTIEF 747
            .||.::.:   |.|        .|..:  |:.:.::..:...:....|    ..:.:.|:|...|
Mouse   203 RTLPSRPR---WERIRERPTFELGSKLSPCFSKPEEAGSHVESVRGRELVKMTETQFVLSFVHRF 264

  Fly   748 -EHDDDTVFFAHSYPYTYSDLQDYLMEIQRH----------PVKSKFCKLRLLCRTLAGNNVYYL 801
             |....|.|||..||::|||.||.|.::.:.          |:.|.:....|||.:|.|..|..|
Mouse   265 VEGRGATTFFAFCYPFSYSDCQDLLSQLDQRFSENYSTHSSPLDSIYYHRELLCYSLDGLRVDLL 329

  Fly   802 TVTA----PSSNEENMRR---------------KKSIVVSARVHPSETPASWMMKGLMDFI-TGD 846
            |:|:    ....|..:.:               |:...:|:||||.|||:|::..|.:||| ..|
Mouse   330 TITSCHGLRDDREPRLEQLFPDLGTPRPFRFTGKRIFFLSSRVHPGETPSSFVFNGFLDFILRPD 394

  Fly   847 TTVAKRLRHKFIFKLVPMLNPDGVIVGNTRNSLTGKDLNRQYRTVIRETYPSIWYTKAMI----- 906
            ...|:.||..|:|||:||||||||:.|:.|....|.:|||||.......:|:|:..||::
Mouse   395 DPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHV 459

  Fly   907 -RRL------------------------------------------------------------- 909
             .||
Mouse   460 HSRLNAKSPTNQQPTLHLPPEAPLSDLEKANNLHNEAHLGQSPDGENPATWPETEPAEEKTDPVW 524

  Fly   910 ------------------IEECGVAMYCDMHAHSRKHNIFIYGCENKRNPEKKLTE-QVFPLMLH 955
                              .:|.|||.|.|:|.|:.|...|:||  |..:.|....| .::|.::.
Mouse   525 LMPQPIPELEEPAPDTIPPKESGVAYYVDLHGHASKRGCFMYG--NSFSDESTQVENMLYPKLIS 587

  Fly   956 KNSADRFSFESCKFKIQ----------RSKEGTGRIVVWML-GITNSYTIEASFG-GSSLGSRKG 1008
            .||| .|.|:.|.|..:          :||||:||:.::.. ||.:|||:|.::. |.|:.|...
Mouse   588 LNSA-HFDFQGCNFSEKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPA 651

  Fly  1009 -----------------THFNTQDYEHMGRAFCETLLDY--CDENPNKILNLLKQQDRLRSKIIE 1054
                             :.:..:.:|.:|||.....||.  |:..|..:|:.......||:.::.
Mouse   652 ACHDNGRASPPPPPAFPSRYTVELFEQVGRAMAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLR 716

  Fly  1055 RLMRE---------GSSADEPLNIPLSDYSSDEGNCSSSSDNEGKHSITTSDLEGPCCAPTRAP- 1109
            .:...         |:|.......|....:|...:||.::.:..:...|.:...|...:...:|
Mouse   717 HVRNSRGLTSAGNMGASKKRGARTPPKSNNSLPVSCSENALSRVRSFSTGTSTGGSSSSQQNSPQ 781

  Fly  1110 ----PSSPEVIHEIRKFRMRRM----RKVMHELDRIYFTPLFQRKFKTLTTLKRRRQKMGVKAAP 1166
                ||.|  .|..|...:..:    :||.|.:    ..|:.:.:...    :||||:      |
Mouse   782 MKNSPSFP--FHGSRTAGLPGLGSSTQKVSHRV----LGPVREPRCSD----RRRRQQ------P 830

  Fly  1167 SGKRLRGGGGPAVSAATPTPAPAVQAAAPVVETNDVQKLHTPRQLARSLPSNSDQPTGGQSSDSS 1231
            ...|      ...|:..|:|..|                             |..||      ||
Mouse   831 LNHR------STTSSLAPSPTLA-----------------------------SSGPT------SS 854

  Fly  1232 ESMDSSQSESLLEPDGSSGSTAASKEVTKKVKTSGAGTKKTAKKKKFMPTEKKKPVVNQKLHVDR 1296
            .:|.|....:.|...|||.|.::|.:..:.|...|         |..:....:.|.:..:|
Mouse   855 RNMGSCLLPNSLSLSGSSCSFSSSGDKPEAVMVIG---------KSLLGAGARIPCIRTRL---- 906

  Fly  1297 NFRLWLANRRIYIYRRKKSTQARRTKVRNKPSKKRGEVVR---TTLDLPTTDPGSDLHFSTDDEE 1358
                                |||....|:.|..:||  :|   .|..:|.|...|:|    :...
Mouse   907 --------------------QARPRLGRSSPPTRRG--MRGSSPTSPIPQTRESSEL----EPGP 945

  Fly  1359 HSPTSGHNGYG--------AVPPLRHTLLQS 1381
            ||.|.|....|        |..|:..||..|
Mouse   946 HSATPGLPQAGPPRPRSAPAFSPISCTLSDS 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nna1	NP_001285225.1	Pepdidase_M14_N	623..758	CDD:407865	44/177 (25%)
		M14_AGBL2-3_like	780..1031	CDD:349478	99/387 (26%)
Agbl5	XP_036020907.1	Pepdidase_M14_N	102..>214	CDD:407865	33/115 (29%)
		M14_AGBL5_like	304..695	CDD:349455	101/393 (26%)