Protein Alignment Nna1 and ccpp-1

DIOPT Version :10

• Sequence 1: NP_001285225.1
• Gene: Nna1 / 32329
• FlyBaseID: FBgn0265726
• Length: 1890
• Species: Drosophila melanogaster
• Sequence 2: NP_491674.2
• Gene: ccpp-1 / 172241
• WormBaseID: WBGene00018995
• Length: 1015
• Species: Caenorhabditis elegans
• Alignment Length: 885
• Identity: 240/885 - (27%)
• Similarity: 387/885 - (43%)
• Gaps: 196/885 - (22%)

  Fly   265 RNSRAASRSEA----------SKDASDIDDIWKNNTSE------------YKPASPRYVLSQFGK 307
            ||.:|..|.|.          :.||||       .||:            :...:.|.......:
 Worm   203 RNGQAIGRYEGFMTRLLVKIKALDASD-------QTSQVLLLDKHLQLLFFTMKNKRTRTQLLRE 260

  Fly   308 NVTKAVIDRIVDHEDLVPPSGSQKVSNQFAVGPVKLPKTNIARLEVAFERSACQDRSK------- 365
            |:.|.:::.:..|  |...|.|:         |.:|    ::.|...|::|.....::
 Worm   261 NICKYLLEVLRRH--LASSSNSR---------PTRL----LSSLFGTFDKSLSAAHTEVVIGTIA 310

  Fly   366 -SRLKKKMSSSRRRRESTSDEDSSSSSLGNEEDEEVDDSDSDAENTGSGIGLRRILGSYSARLAG 429
             .||......:|...::....|..|        .|:.:..||...||.   ..||:.|.||....
 Worm   311 ILRLLSNFKKARDELKNLQVLDICS--------RELKEFWSDEWKTGP---KSRIVDSLSALCLR 364

  Fly   430 GAEKCPCP---------------------GSGSVSDTETLVGDESRSRLAGSNGLHQQDVVCSRN 473
            .....|.|                     |.|.:.::.::.......|.:..:|:.::|....|:
 Worm   365 CMSPLPYPLETRRFPIDFPLPTATPSTPGGHGRIRNSSSINISFDNGRSSDEDGMDEEDEAFVRD 429

  Fly   474 RQAQSRSPLRSVPHTHAATVAAAAAALARGRNRDKDGCLGGKDEKNM-GMGVGTTGTSSMGTRTS 537
            ...:.:.                      .|..|.|   .|||:..: |....||..:.......
 Worm   430 DDDEGKD----------------------DRGSDDD---DGKDDDEINGALPKTTRLNPQQLAKY 469

  Fly   538 SPVRNNVFRLSKDQHIL-----LNSMTSQETTGTLISSTS--------------------TNQTT 577
            :|     |.:..:|..|     :...|:||:..::...|.                    ..:|.
 Worm   470 AP-----FFVENEQGTLQPTFSMIYQTNQESWRSICEKTRHVMPIHHHLPIEMFNTPTRIREKTA 529

  Fly   578 TTTNSSQSFLCSDLPQAQFSRSAVGGARFMTNCHPMNPEEYDG--------------------LE 622
            .|:|:.:..:..:|.:.:  |||......    :.::...:||                    |:
 Worm   530 KTSNNMKKMIIEELDKPE--RSATSNQVI----YDLDTAAFDGLPSPELPFVTGGGKLDTSKDLQ 588

  Fly   623 FESRFESGNLAKAVQITPTYYELYLRPDLYTSRSK-QWFYFRVRRTRRKMLYRFSIVNLVKSDSL 686
            |:||||||||...:|:.||:|||:|.||:...|.. |||:|:|...|:.:.|.|.|||.:||.||
 Worm   589 FDSRFESGNLRMVIQVAPTHYELFLSPDVNQLRDHYQWFFFQVSNMRKSVKYTFEIVNCLKSTSL 653

  Fly   687 YNDGMQPVMYSTLGAKEKSEGWRRCGDNICYYRN---DDESASSSANEDDEDNSTYTLTFTIEFE 748
            |:.||||||||.:   |.:.||||.|:|:||:||   ::.....:..|..:....|::.|.:.|:
 Worm   654 YSQGMQPVMYSMM---ESANGWRRVGENVCYFRNLYINENEEKKNVEEQKKKKYYYSIRFNVTFQ 715

  Fly   749 HDDDTVFFAHSYPYTYSDLQDYLMEIQRHPVKSKFCKLRLLCRTLAGNNVYYLTVTAPSSNEENM 813
            :..|..:.|:.||||||.|...|..:::...::.:|:..::..:||||.:..||:|.|:|..| :
 Worm   716 NTGDICYIAYHYPYTYSFLNSSLSMLKKRKQENVYCREDVIGHSLAGNPIKMLTITTPASAAE-I 779

  Fly   814 RRKKSIVVSARVHPSETPASWMMKGLMD-FITGDTTVAKRLRHKFIFKLVPMLNPDGVIVGNTRN 877
            ..::.||:||||||.||.|||:|:|::: .:...:....|||..||||:|||:|||||..|:.|.
 Worm   780 AAREVIVLSARVHPGETNASWIMQGILENLLCRQSNEMYRLRESFIFKIVPMINPDGVTNGSHRC 844

  Fly   878 SLTGKDLNRQYRTVIRETYPSIWYTKAMIRRLIEECGVA-----MYCDMHAHSRKHNIFIYG--- 934
            ||.|.||||.:.......:|.::.|||:|:.|   |.||     .|.|:|.||:|.:.|:||
 Worm   845 SLAGIDLNRMWDRPNEALHPEVFATKAIIQYL---CEVANKKPFAYVDIHGHSKKWDYFVYGNNA 906

  Fly   935 CENKRNPE------KKLTEQV---FPLMLHKNSADRFSFESCKFKIQRSKEGTGRIVVW-MLGIT 989
            .|:.|..:      .:|.|::   .|..|......||:...|:|.|.|:||.:.|:.|| ..|::
 Worm   907 SESWRADDVLDVGAAQLEEELHLALPKALEATCPSRFNASECRFNITRAKESSARVNVWRQFGVS 971

  Fly   990 NSYTIEASFGGSSLGSRKGTHFNTQDYEHMGRAFCETLLD 1029
            .:||:|::|.|...|...|...||.|.:.:||....:.|:
 Worm   972 TAYTLESTFCGFHKGQNSGYQINTSDLKEIGRDLLHSFLE 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nna1	NP_001285225.1	Pepdidase_M14_N	623..758	CDD:407865	59/138 (43%)
		M14_AGBL2-3_like	780..1031	CDD:349478	99/269 (37%)
ccpp-1	NP_491674.2	Pepdidase_M14_N	589..725	CDD:407865	59/138 (43%)
		Peptidase_M14_like	749..1012	CDD:472171	99/267 (37%)