Protein Alignment Nadsyn and QNS1

DIOPT Version :10

• Sequence 1: NP_572913.1
• Gene: Nadsyn / 32328
• FlyBaseID: FBgn0030512
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_011941.1
• Gene: QNS1 / 856473
• SGDID: S000001116
• Length: 714
• Species: Saccharomyces cerevisiae
• Alignment Length: 703
• Identity: 381/703 - (54%)
• Similarity: 505/703 - (71%)
• Gaps: 9/703 - (1%)

  Fly     1 MGRKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLH 65
            |...:|:|...|||||||||||..||||||..||:.||..|.|||||:.||.|.|||.|.|..||
Yeast     1 MSHLITLATCNLNQWALDFEGNRDRILQSIKIAKERGARLRVGPELEITGYGCLDHFLENDVCLH 65

  Fly    66 SWEVLLEVMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFT 130
            |||:..:::.:.....:::|:||||:|:||.||||:...:.:||.||||:.:.:||||||.|:||
Yeast    66 SWEMYAQIIKNKETHGLILDIGMPVLHKNVRYNCRLLSLDGEILFIRPKIWLANDGNYREMRFFT 130

  Fly   131 AWTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTCLGYEICEELWNVRSKHIEMSLAGVEL 195
            .|.|....|:::||..|.:.|||:.||||||||.:.|||:|.|.||||:..:|.||.|||.|||:
Yeast   131 PWMKPGVVEDFILPPEIQKVTGQRLVPFGDAVINSLDTCIGTETCEELFTPQSPHIAMSLDGVEI 195

  Fly   196 IVNSSGSYMELRKAHITSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQQ 260
            :.|||||:.||||.:...|||.||:.:.||.||::|.|||||.|:|::||:.||:||.|:|:..|
Yeast   196 MTNSSGSHHELRKLNKRLDLILNATKRCGGVYLYANQRGCDGDRLYYDGCALIAINGTIVAQGSQ 260

  Fly   261 FALQDVEVTLATIDLEEIRAYRVSLRSR-CTAAASAAEYPRIHCDFEMSTHSDIFKTSTPP--LN 322
            |:|.||||..||:||||:|:||.::.|| ..|:.:..::.||....|::..:..|..:..|  :.
Yeast   261 FSLDDVEVVTATVDLEEVRSYRAAVMSRGLQASLAEIKFKRIDIPVELALMTSRFDPTVCPTKVR 325

  Fly   323 WPM-HTPEEEIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQQGDAQ 386
            .|. |:||||||||||||:||||||....|||||||||:||.::|.|||||||.:..|.|.|:.|
Yeast   326 EPFYHSPEEEIALGPACWMWDYLRRCNGTGFFLPLSGGIDSCATAMIVHSMCRLVTDAAQNGNEQ 390

  Fly   387 VLHDIRQLL-ADSDYTPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQLANQLGSYHIEISIDSA 450
            |:.|:|::. :..|:.||:...|.:::..:|:||:.|||||||.||..|:|.:||||:::.:||.
Yeast   391 VIKDVRKITRSGDDWIPDSPQDLASKIFHSCFMGTENSSKETRNRAKDLSNAIGSYHVDLKMDSL 455

  Fly   451 VNALLSIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQLTLWVRNRP--GGLLVL 513
            |::::|:|...||..|.::..||...:||||||:|:|:||||:|:||||..|||..|  ||||||
Yeast   456 VSSVVSLFEVATGKKPIYKIFGGSQIENLALQNIQARLRMVLSYLFAQLLPWVRGIPNSGGLLVL 520

  Fly   514 GSANVDESLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLESIIDAPPTAELEPL 578
            |||||||.|||||||||||||||||||||||.||:||:.||..::|:|:|...::|.|||||||:
Yeast   521 GSANVDECLRGYLTKYDCSSADINPIGGISKTDLKRFIAYASKQYNMPILNDFLNATPTAELEPM 585

  Fly   579 QENGELQQTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLSPKEVAEKVKHFFLC 643
            .:  :..|:||.||||||.||..||.|||...|||||||..|:..|...|:|::::||||.||..
Yeast   586 TK--DYVQSDEIDMGMTYEELGVFGYLRKVEKCGPYSMFLKLLHQWSPKLTPRQISEKVKRFFFF 648

  Fly   644 YAINRHKMTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEKLQ 696
            |||||||.||||||.|||.|||:|||||.||||..|.:.|..:.||:..|:.:
Yeast   649 YAINRHKQTVLTPSYHAEQYSPEDNRFDLRPFLINPRFPWASRKIDEVVEQCE 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nadsyn	NP_572913.1	PLN02339	3..695	CDD:177973	380/698 (54%)
QNS1	NP_011941.1	PLN02339	4..704	CDD:177973	380/700 (54%)