Protein Alignment Nadsyn and Nadsyn1

DIOPT Version :10

• Sequence 1: NP_572913.1
• Gene: Nadsyn / 32328
• FlyBaseID: FBgn0030512
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_852145.2
• Gene: Nadsyn1 / 353255
• RGDID: 727801
• Length: 725
• Species: Rattus norvegicus
• Alignment Length: 732
• Identity: 435/732 - (59%)
• Similarity: 536/732 - (73%)
• Gaps: 16/732 - (2%)

  Fly     1 MGRKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLH 65
            ||||||||...|||||||||||..|||:||..||..||.||.|||||:|||.|.||:.|.||.||
  Rat     1 MGRKVTVATCALNQWALDFEGNFQRILKSIQIAKGKGARYRLGPELEICGYGCWDHYHESDTLLH 65

  Fly    66 SWEVLLEVMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFT 130
            |.:||..::.:|..::::.|||||:|||||.|||||.|.||:|||||||||:.::|||||.||||
  Rat    66 SLQVLAALLDAPATQDIICDVGMPIMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFT 130

  Fly   131 AWTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTCLGYEICEELWNVRSKHIEMSLAGVEL 195
            .|.::.||||||||||:...|.|:||||||.|:||:|||:|.|||||||...|.|:.|.|.|||:
  Rat   131 PWARSRQTEEYVLPRMLQDLTKQKTVPFGDVVLATQDTCIGSEICEELWTPCSPHVNMGLDGVEI 195

  Fly   196 IVNSSGSYMELRKAHITSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQQ 260
            |.|:|||:..|||||...||:..|:.|.||.||.:|.:||||.|:|::||:.||:||.|.|:..|
  Rat   196 ITNASGSHHVLRKAHTRVDLVTMATSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSIFAQGTQ 260

  Fly   261 FALQDVEVTLATIDLEEIRAYRVSLRSRCTAAASAAEYPRIHCDFEMSTHSDIFKTSTPPLNWPM 325
            |:|.||||..||:|||::|:||..:.||...|.....|||:..||.:|...|:.:..:.|:.|..
  Rat   261 FSLDDVEVLTATLDLEDVRSYRAEISSRNLEATRVNPYPRVTVDFALSVSEDLLEPVSEPVEWTY 325

  Fly   326 HTPEEEIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQQGDAQVLHD 390
            |.|||||:|||||||||:||||.|.||||||||||||::||.:|:|||..:.:||:.|:.|||.|
  Rat   326 HRPEEEISLGPACWLWDFLRRSNQAGFFLPLSGGVDSAASACVVYSMCCLVCEAVKSGNQQVLTD 390

  Fly   391 IRQLLADSDYTPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQLANQLGSYHIEISIDSAVNALL 455
            ::.|:.:|.|||.:...||.|||.||||.|.|||:||..||.:||.|:|||||.::||.||.|:|
  Rat   391 VQNLVDESSYTPQDPRELCGRLLTTCYMASENSSQETHNRATKLAQQIGSYHISLNIDPAVKAIL 455

  Fly   456 SIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQLTLWVRNRPGGLLVLGSANVDE 520
            .||:.|||..|||...||.:|:||||||:|:||||||||:||||:||.|...|.|||||||||||
  Rat   456 GIFSLVTGKFPRFSAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGARGSLLVLGSANVDE 520

  Fly   521 SLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLESIIDAPPTAELEPLQENGELQ 585
            ||.|||||||||||||||||||||.|||.|:....::|.||||::|:.||.|||||||.: |::.
  Rat   521 SLLGYLTKYDCSSADINPIGGISKTDLRAFVQLCAERFQLPVLQAILSAPATAELEPLAD-GQVS 584

  Fly   586 QTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLSPKEVAEKVKHFFLCYAINRHK 650
            |.||.||||||.|||.||||||.:..|||||||.|:..||...:|::||||||.||..|:|||||
  Rat   585 QMDEEDMGMTYTELSIFGRLRKVAKAGPYSMFCKLLNMWKDSCTPRQVAEKVKRFFSKYSINRHK 649

  Fly   651 MTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEKLQPIYTPSSAQLRPSSEDLLI 715
            ||.|||:.|||:|||||||||.|||||...|.|||..||::..:|:          |.:|:.|
  Rat   650 MTTLTPAYHAENYSPDDNRFDLRPFLYNTRWPWQFLCIDNQVVQLE----------RKTSQTL-- 702

  Fly   716 STQRSSHLDDSKHSSPL 732
            ..|...|.   |..||:
  Rat   703 EEQIQEHF---KEPSPI 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nadsyn	NP_572913.1	PLN02339	3..695	CDD:177973	424/691 (61%)
Nadsyn1	NP_852145.2	PLN02339	3..698	CDD:177973	426/705 (60%)
		Ligase. /evidence=ECO:0000250	325..706		244/393 (62%)