Protein Alignment Nadsyn and qns-1

DIOPT Version :9

• Sequence 1: NP_001285224.1
• Gene: Nadsyn / 32328
• FlyBaseID: FBgn0030512
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001255472.1
• Gene: qns-1 / 177900
• WormBaseID: WBGene00007698
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 331/717 - (46%)
• Similarity: 451/717 - (62%)
• Gaps: 46/717 - (6%)

  Fly     3 RKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLHSW 67
            |:..||..|:|.|||||:||..||:::..||..:||..|.|||||:.||.|.|||.|.||..|||
 Worm     6 RRCRVATCTVNNWALDFKGNYERIVKTCEEAAALGARIRLGPELEIPGYGCADHFFELDTERHSW 70

  Fly    68 EVLLE-VMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFTA 131
            |:|.: |..|....|:||..|:|...|.:.|||..|..|.::|.||.||.:.||..|||||||..
 Worm    71 EMLSKLVEKSKKWPNLLVVTGLPTRFRGLLYNCAAALRNGKLLFIRAKMGLADDNVYRESRWFVK 135

  Fly   132 WTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTC-LGYEICEELWNVRSKHIEMSLAGVEL 195
            ||:..  :.|.:|.....|..|:||||||.::.:.|.. :|:|||||||:.||.::.::..||::
 Worm   136 WTETF--KHYQMPLNSDIHFDQETVPFGDGILESSDNVRIGFEICEELWSARSTNVRLAEQGVDI 198

  Fly   196 IVNSSGSYMELRKAHI-TSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQ 259
            :.|.|||:..|.|::. .:.||..:|.|.||.||::|.|||||.|||::|.|::|.||::||:..
 Worm   199 MCNGSGSHHILGKSNYRINQLILGSSAKVGGVYLYANQRGCDGDRVYYDGASSVAQNGDLLAQIH 263

  Fly   260 QFALQDVEVTLATIDLEEIRAYR-VSLRSRCTAAASAAEYPRIHCDFEMSTHSDIFKTSTPPLNW 323
            ||.::|..|..|.:||.:.:.:| :....|..|:......| |..|.:|:......:.||.|:
 Worm   264 QFDIEDTSVVSAVVDLSDNQCFRHMKSSDRGNASDQVTVVP-IRFDGKMTGGIKYNEKSTAPI-- 325

  Fly   324 PMHTPEE-------EIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQ 381
              |..|:       |:..||..:||.||||||..|:|:|||||.|||:.|.:|..||.::..|::
 Worm   326 --HNVEDLQLSPIAELCHGPPAYLWTYLRRSGMAGYFIPLSGGQDSSAVAAMVRLMCEKVCGAIK 388

  Fly   382 Q------GDAQVLHDIRQLLADSDY------TPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQL 434
            :      ||            |..|      ..::.|.|||::|.||||.|.:||.|||:.|..|
 Worm   389 RRRETDGGD------------DPAYYLGGKKVGEDPAELCNQVLFTCYMASEHSSDETRQCAEGL 441

  Fly   435 ANQLGSYHIEISIDSAVNALLSIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQL 499
            |..:.|.|..|.||:.|.::|.:||...|..|.|::...  |:.:||||:|:||||||:|:||||
 Worm   442 AKNVNSSHCGIFIDTIVTSILKVFNVAYGFMPSFQSPDN--RETMALQNIQARIRMVLSYLFAQL 504

  Fly   500 TLWVRNRPGGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLE 564
            .|....|||||||||:|||||||.|||||||||||||||||.:||.|||:||..|.:|:.:..|.
 Worm   505 ALVSHKRPGGLLVLGTANVDESLVGYLTKYDCSSADINPIGSVSKRDLRQFLEIAYEKYGMAALR 569

  Fly   565 SIIDAPPTAELEPLQENGELQQTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLS 629
            .:||:.|||||:||.: |::.|||||::|:||.|||..|||||....|||.||..|:..|....|
 Worm   570 CVIDSTPTAELKPLVD-GKVAQTDEAEIGLTYDELSVIGRLRKPGGMGPYGMFLKLLQLWGDKYS 633

  Fly   630 PKEVAEKVKHFFLCYAINRHKMTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEK 694
            ..|:.|||..||..|.:||||.||.||::|||:|||||:|.||||||| |::|:||:.|.::..:
 Worm   634 IDEIEEKVNKFFWRYRVNRHKATVSTPAIHAENYSPDDHRNDHRPFLY-PDFSYQFERIREKVVE 697

  Fly   695 LQ 696
            |:
 Worm   698 LK 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nadsyn	NP_001285224.1	PLN02339	3..695	CDD:177973	330/714 (46%)
qns-1	NP_001255472.1	PLN02339	6..702	CDD:177973	331/717 (46%)
		GAT_Gln-NAD-synth	9..298	CDD:143594	129/290 (44%)
		NAD_synthase	334..654	CDD:238309	164/334 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158457
Domainoid	1	1.000	259	1.000	Domainoid score	I1078
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	606	1.000	Inparanoid score	I501
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54707
OrthoDB	1	1.010	-	-		D113573at33208
OrthoFinder	1	1.000	-	-		FOG0004683
OrthoInspector	1	1.000	-	-		oto19845
orthoMCL	1	0.900	-	-		OOG6_100679
Panther	1	1.100	-	-	LDO	PTHR23090
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R791
SonicParanoid	1	1.000	-	-		X3872
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940