DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11158 and si:dkey-4e7.3

DIOPT Version :9

Sequence 1:	NP_572912.1	Gene:	CG11158 / 32327	FlyBaseID:	FBgn0030511	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_005167497.1	Gene:	si:dkey-4e7.3 / 402865	ZFINID:	ZDB-GENE-070912-542	Length:	388	Species:	Danio rerio

Alignment Length:	321	Identity:	114/321 - (35%)
Similarity:	158/321 - (49%)	Gaps:	37/321 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DCDIGTDDAWGLAMLLRAEELTLREGRTCKVLAITTVHGNTDADNGTLNALRVLHTLNRRDVPVF 75
            |.|.|.|||..:.|.|....:        ::|.|:.|||||..:|...|.||:|......::|||
Zfish    78 DVDCGVDDAQAIMMALAVPGV--------QILGISCVHGNTSVENVCKNVLRILKVCKHLEIPVF 134

  Fly    76 RGCYESIVPRTWEYTNCFHGQDGLNDVGN--YPVVDVEQELQPEHAVNAMYRLARANPGQVDFLL 138
            ||..:.::.:. ..|..|||:|||.|..:  .|.:|:   :|.|.||:||.|:...|||:|..:.
Zfish   135 RGANKPLLGQV-VGTGDFHGKDGLGDAPDPEAPGLDL---VQKEGAVSAMIRIVNENPGEVSLVA 195

  Fly   139 CGPLTNFANCINLYGNSFLTNIGRVYIMGGNIFGKGNVTKSAEFNFMMDPEAAHITLERLLEPAI 203
            ..||||.|..:.| ..|....:..:||||||...:||.|...||||..|||||:|.|.....|..
Zfish   196 TAPLTNVALAVKL-DPSLPQKLKGLYIMGGNTDSRGNTTMCGEFNFAADPEAAYIVLNEFTCPVY 259

  Fly   204 I----------LPWEPCIDGEFDTTLDWRLNVLGAVDHPFIELLT-RVERSMLEPRGFVKWISCD 257
            |          ||||.| ||......|....:.....|......: |:|:.::..:||   ||||
Zfish   260 IAAWEFTCHSKLPWEFC-DGWLAQDTDKARFMKQIFQHSMKNSYSERIEKELVAGQGF---ISCD 320

  Fly   258 SLLTAAYLFPDAMIAEQRQYYATVELSGIHTRGQMVLDHLRGRKVDDIHGKKINVHIIRRL 318
            |...||.: .|.:|.|..:...||||:|...||.||:|||      |:..|....||::::
Zfish   321 SYAIAAAI-DDTIILESLERAVTVELAGNCCRGMMVVDHL------DLLQKTHKAHILKKV 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11158	NP_572912.1	nuc_hydro_CeIAG	6..328	CDD:239115	114/321 (36%)
si:dkey-4e7.3	XP_005167497.1	nuc_hydro_CeIAG	73..384	CDD:239115	114/321 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592943
Domainoid	1	1.000	155	1.000	Domainoid score	I4174
eggNOG	1	0.900	-	-		E1_COG1957
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H70970
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4266
OMA	1	1.010	-	-		QHG62281
OrthoDB	1	1.010	-	-		D422700at33208
OrthoFinder	1	1.000	-	-		FOG0001175
OrthoInspector	1	1.000	-	-		mtm6574
orthoMCL	1	0.900	-	-		OOG6_100640
Panther	1	1.100	-	-	O	PTHR46190
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X724
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770