Protein Alignment CG11162 and CH25H

DIOPT Version :10

• Sequence 1: NP_572910.1
• Gene: CG11162 / 32325
• FlyBaseID: FBgn0030509
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_003947.1
• Gene: CH25H / 9023
• HGNCID: 1907
• Length: 272
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 72/267 - (26%)
• Similarity: 107/267 - (40%)
• Gaps: 42/267 - (15%)

  Fly    14 YLQDKWTLLLDTVGEESWRLWVVGSTVVIFIVYWLYAGI---FTLMDI-TNRPRFLRKYKIQPG- 73
            :||..|..|      .||...:......:......|.|.   |.::|| .:....||:|||.|.
Human    19 FLQPLWDHL------RSWEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVPALRRYKIHPDF 77

  Fly    74 -----QNEPVNLAKLWHAVKVVLFNLTVVNFLVSWVVYEFVYKSENSQDIRVLPTFKRSLRDLVV 133
                 |..|.....|:..|..| |.:|    |:.|.....:...|       .|.....|..::.
Human    78 SPSAQQLLPCLGQTLYQHVMFV-FPVT----LLHWARSPALLPHE-------APELLLLLHHILF 130

  Fly   134 FVVLEEIMFYYAHRLLHHRS--VYKYVHKKHHEWTAPIAAITLYAHPVEHVLANLLPVATSIAIL 196
            .::|.::.|:..| ||||:.  :|:..||.||:.::..|..|.|....|........: .::.:|
Human   131 CLLLFDMEFFVWH-LLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDM-MNVTLL 193

  Fly   197 GTHVALAYVIFALAIINSMSDHTGYSFPWSA---------GSVRFHDYHHAKFNYNYG-VLGFLD 251
            |.|.........:.|..|:.||:||:||||.         |.|..||.||:.||.|:. .....|
Human   194 GCHPLTTLTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWD 258

  Fly   252 KLHGTYR 258
            |:.||.|
Human   259 KILGTLR 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11162	NP_572910.1	FA_hydroxylase	131..256	CDD:397991	40/136 (29%)
CH25H	NP_003947.1	FA_hydroxylase	135..263	CDD:397991	39/129 (30%)
		Histidine box-1	142..146		2/4 (50%)
		Histidine box-2	157..161		2/3 (67%)
		Histidine box-3	238..244		3/5 (60%)