Protein Alignment CG11162 and ERG25

DIOPT Version :10

• Sequence 1: NP_572910.1
• Gene: CG11162 / 32325
• FlyBaseID: FBgn0030509
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_011574.3
• Gene: ERG25 / 852951
• SGDID: S000003292
• Length: 309
• Species: Saccharomyces cerevisiae
• Alignment Length: 300
• Identity: 77/300 - (25%)
• Similarity: 132/300 - (44%)
• Gaps: 43/300 - (14%)

  Fly     5 LAGWTQSGDYLQDKWTLLLDTVG---------EESWRLW-------VVGSTVVIFIVY-WLYAGI 52
            |:|..|:..|.|     .|..|.         |:.|..|       |:.:.::.|::: ::|  .
Yeast    10 LSGLVQASTYSQ-----TLQNVAHYQPQLNFMEKYWAAWYSYMNNDVLATGLMFFLLHEFMY--F 67

  Fly    53 FTLMD--ITNRPRFLRKYKIQPGQNEPVNLAK-LWHAVKVVLFNLTVVNFLVSWVVYEFVYKSEN 114
            |..:.  |.::..:.|::|:||.:   :..|| ..:.:|.||.:..:|..:..|..:....|...
Yeast    68 FRCLPWFIIDQIPYFRRWKLQPTK---IPSAKEQLYCLKSVLLSHFLVEAIPIWTFHPMCEKLGI 129

  Fly   115 SQDIRVLPTFKRSLRDLVVFVVLEEIMFYYAHRLLHHRSVYKYVHKKHHEWTAPIAAITLYAHPV 179
            :.:: ..|:.|....::.:|.|||:...|:||||.|:...|||:||:||.:.||......||||.
Yeast   130 TVEV-PFPSLKTMALEIGLFFVLEDTWHYWAHRLFHYGVFYKYIHKQHHRYAAPFGLSAEYAHPA 193

  Fly   180 EHVLANL----LPVATSIAILGTHVALAYVIFALAIINSMSDHTGYSFPWSAGSV-------RFH 233
            |.:....    :|:...:.....|:....|...|.:..::..|:||.||||...:       ..|
Yeast   194 ETLSLGFGTVGMPILYVMYTGKLHLFTLCVWITLRLFQAVDSHSGYDFPWSLNKIMPFWAGAEHH 258

  Fly   234 DYHHAKFNYNY-GVLGFLDKLHGTYRAPAEQKAPSQRIKK 272
            |.||..|..|| ....:.|....|...|..:.:..:|:||
Yeast   259 DLHHHYFIGNYASSFRWWDYCLDTESGPEAKASREERMKK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11162	NP_572910.1	FA_hydroxylase	131..256	CDD:397991	43/136 (32%)
ERG25	NP_011574.3	FA_hydroxylase	147..282	CDD:397991	43/134 (32%)