DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11164 and rnaseh2b

DIOPT Version :9

Sequence 1:	NP_001285220.1	Gene:	CG11164 / 32323	FlyBaseID:	FBgn0030507	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_012812404.1	Gene:	rnaseh2b / 549083	XenbaseID:	XB-GENE-1004443	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	91/290 - (31%)
Similarity:	137/290 - (47%)	Gaps:	37/290 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PGHGKEALFITHPDGRMM-ELVAFTEPRRSWFVDSEVCSNGRIYMTAPVDPTFLALHHLRKHCAQ 120
            |...|.::|:....|:.: |:.||.|..||||:...|..:||:.:..|:||.||.||:|.|...:
Frog    49 PCTDKGSMFLFIDSGQQICEVKAFHEEYRSWFIGQTVQQDGRLLIATPIDPMFLVLHYLIKADKE 113

  Fly   121 RA--ISLDNIAVEE--ASTSRLLNEILDPGNLKCVADVKSSGEQKFYKYNQERTLAWLALKTRQV 181
            :.  ..::.|.|:|  .|.|.||.......:|..|.:.|..|.:|||||::|:||.||..|....
Frog   114 QGKFQPVEQIVVDEEFPSCSMLLQCTPVSKSLHHVTEEKEIGSKKFYKYSKEKTLVWLKKKVELT 178

  Fly   182 AKILKEKQVHCGHSAQSQNFVRSEKLVAENVSNEMDYTRMACDYVGRYLDADLHGLLTSYLHIPS 246
            .|:||...:..|...||..|:|:.:  ..:|..| ||||.|...:..||..||...|:.||.:|
Frog   179 VKVLKSSNICVGGGVQSATFIRNTQ--GSDVKEE-DYTRYAHGLISEYLTEDLREDLSKYLGLP- 239

  Fly   247 EIQAIVEEKAASQKRKSVAGKNEGSDSKKIKLNESDAAAKLKSSGLVDSDGDPNATITSPTAAPL 311
            ::.:...|....:::.|.|......|..|.   .||:..|..:|
Frog   240 DLSSPTPEPPVKKRKVSEAPVEAEEDYTKF---NSDSKNKKSNS--------------------- 280

  Fly   312 KERSLTAKEKALAKGAK-GTKSIASFFKAK 340
               .:||.:|:|||..| |.|:|::||..|
Frog   281 ---KMTAAQKSLAKVDKSGMKNISAFFSPK 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11164	NP_001285220.1	RNase_H2-B	39..338	CDD:187751	89/286 (31%)
rnaseh2b	XP_012812404.1	RNase_H2-B	30..305	CDD:187751	89/286 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9728
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41572
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4687
OMA	1	1.010	-	-		QHG59373
OrthoDB	1	1.010	-	-		D1092212at2759
OrthoFinder	1	1.000	-	-		FOG0005677
OrthoInspector	1	1.000	-	-		oto103644
Panther	1	1.100	-	-	LDO	PTHR13383
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10927
SonicParanoid	1	1.000	-	-		X6122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110