Protein Alignment DNAlig4 and LIG1

DIOPT Version :10

• Sequence 1: NP_572907.1
• Gene: DNAlig4 / 32322
• FlyBaseID: FBgn0030506
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_172293.2
• Gene: LIG1 / 837333
• AraportID: AT1G08130
• Length: 790
• Species: Arabidopsis thaliana
• Alignment Length: 610
• Identity: 149/610 - (24%)
• Similarity: 236/610 - (38%)
• Gaps: 104/610 - (17%)

  Fly    59 PEDGASSFYSVLRLLLPGAD-----TGRDTYGLQIT-ALGRLYIRVLQLPTDSSDAIRLQHRNGN 117
            |||..::.|.....:.|..:     .|..|....|: |.||....|.:..|:..|.       |.
plant   212 PEDLVATVYLSANEIAPAHEGVELGIGESTIIKAISEAFGRTEDHVKKQNTELGDL-------GL 269

  Fly   118 MYRDYGDVVYSVLKPRCFNPPSNLRLKEIHQMLDTIANEDTEVKQQQLIRFTEQASPE-EQKWLI 181
            :.:........:.||   .|.:.:::.:..:.:...:.:|:..|::..::....|:.: |..:|.
plant   270 VAKGSRSTQTMMFKP---EPLTVVKVFDTFRQIAKESGKDSNEKKKNRMKALLVATTDCEPLYLT 331

  Fly   182 RLLLKSLGLGIGEQKIFGVLHPKAQDIYQRCSDLGHVCNLLADRTTDLDASSSKDSKAAVKFVNL 246
            |||...|.||...|.:...|...|  :|.             :..:....::....:.|.|.|..
plant   332 RLLQAKLRLGFSGQTVLAALGQAA--VYN-------------EEHSKPPPNTKSPLEEAAKIVKQ 381

  Fly   247 NSVIRPFHQ-------------------------IRPMLCERFPG--DIQELMQSDVLYLETKMD 284
            ...:.|.:.                         |.|||.:...|  :|....|..|...|.|.|
plant   382 VFTVLPVYDIIVPALLSGGVWNLPKTCNFTLGVPIGPMLAKPTKGVAEILNKFQDIVFTCEYKYD 446

  Fly   285 GERFQLH-IDRGRFMYISRNGVDYTRNFGHSYDHGTLTPKLRGLLPLGLESIILDGEMMVWDTNK 348
            |||.|:| ::.|.|...|||.   .||.|...|......:|:   ...::|.|||.|::.:|..|
plant   447 GERAQIHFMEDGTFEIYSRNA---ERNTGKYPDVALALSRLK---KPSVKSFILDCEVVAFDREK 505

  Fly   349 ---LRFR----EKGENTDVKSLKPEGSWQPCFVVYDLLYFNGQSLLDHTYIQRAYKLQKLIVEQS 406
               |.|:    ...:|.:|..:|.    ..|...:|:||.|||.|:......|..||.:...|..
plant   506 KKILPFQILSTRARKNVNVNDIKV----GVCIFAFDMLYLNGQQLIQENLKIRREKLYESFEEDP 566

  Fly   407 GVLQLMRARKIGSVQEFNELFQQALDSHAEGIVLKKQGS--RYQPGVRLGGGWYKDKADYIKGLI 469
            |..|...|.....:.|..:....::|...||:::|...|  .|:|..| ...|.|.|.||:..:.
plant   567 GYFQFATAVTSNDIDEIQKFLDASVDVGCEGLIIKTLDSDATYEPAKR-SNNWLKLKKDYMDSIG 630

  Fly   470 TEFDVLIIGAFYNR-KRTFV-DSFLLGVLQPAPPGSSNRPEVFSIGVVANNTKQRGVLNHTLKPH 532
            ...|::.|.||:.| |||.| .:|||...      ..::.|..||..:...... .:|:......
plant   631 DSVDLVPIAAFHGRGKRTGVYGAFLLACY------DVDKEEFQSICKIGTGFSD-AMLDERSSSL 688

  Fly   533 WHDVVNEPPPLWFHYKPKERSGCPDLWIEPQNSVILQVKAADL-------APNGAFFTRK--SLH 588
            ...|:..|..   :|:..: |..||:|.||  :.:.:||||||       |..|.....|  ||.
plant   689 RSQVIATPKQ---YYRVGD-SLNPDVWFEP--TEVWEVKAADLTISPVHRAATGIVDPDKGISLR 747

  Fly   589 FPRTEMKRDDKTWSECMTLKEFNDL 613
            |||....|:||...|..:.::..||
plant   748 FPRLLRVREDKKPEEATSSEQIADL 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig4	NP_572907.1	dnl1	84..613	CDD:273147	140/578 (24%)
		Adenylation_DNA_ligase_IV	249..466	CDD:185713	68/253 (27%)
		BRCT	670..760	CDD:469589
		BRCT_2	830..917	CDD:465186
LIG1	NP_172293.2	PLN03113	49..790	CDD:215584	149/610 (24%)