Protein Alignment DNAlig4 and DNAlig1

DIOPT Version :9

• Sequence 1: NP_572907.1
• Gene: DNAlig4 / 32322
• FlyBaseID: FBgn0030506
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Alignment Length: 634
• Identity: 150/634 - (23%)
• Similarity: 247/634 - (38%)
• Gaps: 111/634 - (17%)

  Fly    59 PEDGASSFYSVLRLLLPGADTGRDTYGLQITALGRLYIRVLQLPTDSSDA-IRLQHRNGNMYRDY 122
            |||...|.|..:..|.|..:      ||::.......::.:...|..:.| |:.|.:   :..|.
  Fly   162 PEDLVPSVYLSINQLAPAYE------GLELGVAETTLMKAICKATGRNLAHIKSQTQ---LTGDL 217

  Fly   123 GDVV-YSVLKPRCFNPPSNLRLKEIHQMLDTIANEDTEVKQQQLIRFTEQASPEEQKWLIRLLLK 186
            |.|. .|.:..|....|:.|.::::.:.|..||....:.|...:..........|.::.||.|:.
  Fly   218 GIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQSKMDLVYNMFVACRSSEARFFIRSLIG 282

  Fly   187 SLGLGIGEQKIFGVLHPKAQDIYQRCSDLGHVCNLLADRTTDLDASSSKDSKAAVKFV-----NL 246
            .|.:||.||.:...|   |..:.::    .|:.:..|.:..|:......|:...:|..     |.
  Fly   283 KLRIGIAEQSLLTAL---AIGLVKK----NHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNY 340

  Fly   247 NSVIR--------------PFH---QIRPMLC----------ERFPGDIQELMQSDVLYLETKMD 284
            :.:|.              |.|   .:||||.          |||.|     ||   :..|.|.|
  Fly   341 DIIIPAILKYDIKELQERCPMHPGMPLRPMLAQPTKGVHEVFERFGG-----MQ---ITCEWKYD 397

  Fly   285 GERFQLH-IDRGRFMYISRNGVDYTRNFGHSYDHGTLTPKLRGLLPLGLESIILDGEMMVWDTNK 348
            |||.|:| .::|.....|||..:.|..:      ..|..:...||...::|.|:|.|::.||..:
  Fly   398 GERAQIHRNEKGEISIFSRNSENNTAKY------PDLIARSTALLKGDVKSYIIDSEIVAWDVER 456

  Fly   349 ---LRFR----EKGENTDVKSLKPEGSWQPCFVVYDLLYFNGQSLLDHTYIQRAYKLQKLIVEQS 406
               |.|:    .|.:|.|::.:|.    |.|..::||||.||.:|:.....:|...|.:...|..
  Fly   457 KQILPFQVLSTRKRKNVDIEEIKV----QVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVE 517

  Fly   407 GVLQLMRARKIGSVQEFNELFQQALDSHAEGIVLK--KQGSRYQPGVRLGGGWYKDKADYIKGLI 469
            |..:...|.....:.|..:..::::..:.||:::|  .:.:.|:...| ...|.|.|.||:..:.
  Fly   518 GEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKR-SRNWLKLKKDYLSNVG 581

  Fly   470 TEFDVLIIGAFYNRKR---TFVDSFLLGVLQPAPPGSSNRPEVFSIGVVANNTKQRGVLNHT--L 529
            ...|:::||.:..:.|   |: ..|||...      .:...|..||..:........:..|:  |
  Fly   582 DSLDLVVIGGYKGKGRRTGTY-GGFLLACY------DTENEEYQSICKIGTGFTDEDLQTHSEFL 639

  Fly   530 KPHWHDVVNEPPPLWFHYKPKERSGCPDLWIEPQNSVILQVKAADL-------APNGAFFTRK-- 585
            ..|    |......::.|.|...   ||.|.||..  :.:||.|||       |..|.....:
  Fly   640 GKH----VTSAAKSYYRYDPSLE---PDHWFEPVQ--VWEVKCADLSLSPIHRAAIGIVDGERGI 695

  Fly   586 SLHFPRTEMKRDDKTWSECMTLKEFNDLCGGPLAIKKLNK--RQLRLED 632
            ||.|||....||||.........:...:......:|...|  .|:.:||
  Fly   696 SLRFPRFIRIRDDKNSENATDANQVAHMYQSQDQVKNNQKSSTQMEMED 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig4	NP_572907.1	DNA_ligase_A_N	10..197	CDD:282522	33/139 (24%)
		dnl1	84..613	CDD:273147	138/586 (24%)
		Adenylation_DNA_ligase_IV	249..466	CDD:185713	66/253 (26%)
		OBF_DNA_ligase_IV	469..607	CDD:153437	38/151 (25%)
		BRCT	668..745	CDD:214602
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	150/634 (24%)
		DNA_ligase_A_N	126..292	CDD:282522	32/138 (23%)
		Adenylation_DNA_ligase_I_Euk	358..576	CDD:185710	63/236 (27%)
		OBF_DNA_ligase_I	581..726	CDD:153438	38/160 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442864
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1793
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750