DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment DNAlig4 and Lig1

DIOPT Version :10

Sequence 1:	NP_572907.1	Gene:	DNAlig4 / 32322	FlyBaseID:	FBgn0030506	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_034845.3	Gene:	Lig1 / 16881	MGIID:	101789	Length:	916	Species:	Mus musculus

Alignment Length:	17	Identity:	6/17 - (35%)
Similarity:	10/17 - (58%)	Gaps:	0/17 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 TTYSNPRKRESDEEQKP 227
            ||::..||...:..:||
Mouse     8 TTHNQSRKWHRNGIKKP 24

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig4	NP_572907.1	dnl1	84..613	CDD:273147	6/17 (35%)
		Adenylation_DNA_ligase_IV	249..466	CDD:185713
		BRCT	670..760	CDD:469589
		BRCT_2	830..917	CDD:465186
Lig1	NP_034845.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..197		6/17 (35%)
		PLN03113	171..912	CDD:215584
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..266
		Interaction with target DNA. /evidence=ECO:0000250	447..456
		Interaction with target DNA. /evidence=ECO:0000250	640..642
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	879..916
Blue background indicates that the domain is not in the aligned region.

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