Protein Alignment NFAT and nfatc1

DIOPT Version :9

• Sequence 1: NP_001096974.1
• Gene: NFAT / 32321
• FlyBaseID: FBgn0030505
• Length: 1457
• Species: Drosophila melanogaster
• Sequence 2: XP_012820381.1
• Gene: nfatc1 / 780197
• XenbaseID: XB-GENE-876756
• Length: 945
• Species: Xenopus tropicalis
• Alignment Length: 1054
• Identity: 240/1054 - (22%)
• Similarity: 391/1054 - (37%)
• Gaps: 233/1054 - (22%)

  Fly    73 AYQHHY---KSNFGMRMTMS-TNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPG 133
            |.:.|:   .||....:::. |||::|              .|..||......|:
 Frog    41 AEEEHFNYASSNLSASLSLGVTNSSLS--------------NPCHGLQSSNPVIS---------- 81

  Fly   134 KRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNT 198
             .||...|||                      |.||..|..|.|...|.|            ...
 Frog    82 -IIPSSSHPP----------------------GYGGNLDSEATGYYLSPS------------IRP 111

  Fly   199 VAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRS 263
            |...|..:.....::.|..|..|:|...:...::                        |||.::.
 Frog   112 VGPPALESPRIEITSCLAMHPNHNQFFNEPDIEE------------------------AIPQAKR 152

  Fly   264 RNNTKVMAHCLEDLD-------LISASSEDSSTIATPAGLDEDTGFVNDTKTTTTGGNS------ 315
            .::|..:.  |.::|       |..|||..|.:..:.|...|.......|...|:...|
 Frog   153 IHSTATLN--LPNVDTYRDPSCLSPASSLSSRSCNSEASSFESNYSYPFTSPQTSPWQSPCVSPK 215

  Fly   316 SSDPFGGVFQATEAAVAAAVNAFNLQQQQHSVQQQQHQLFQYNGLLLQPQQQ-----LQQQQSHH 375
            ::||       .|....:.|....|...:||..............|..|..:     ::::.|.:
 Frog   216 TTDP-------EEGYQRSMVTCTLLSSPRHSPSTSPRTSISEENWLNAPSSRPSSPCIKRKYSLN 273

  Fly   376 QQQQQQQQHH--RHGKHIKRKKLECNQVELDNDDACSEDEFIRKIASSVTMSPTLEATPSPPPIV 438
            .:|.....||  ....|...:....::..|.|....:....:..| :::|..||......|....
 Frog   274 GRQTSYSPHHSPTPSPHNSPRVSVTDETWLGNTHQYTSSAIVAAI-NALTTDPTDMNDGIPIKSR 337

  Fly   439 ASVAPATTIVSLL--PLISSGNSNNNNNN--------------NNIETKFISA----------RN 477
            .:.|..|..:||.  |:....::.::.|:              .|...:::|.          :|
 Frog   338 KTAADHTPNMSLKTEPVCDDHSTMSSTNDLSPDDYSGFHHIRKGNFCDQYLSVPQQSYQWAKPKN 402

  Fly   478 VTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTG 542
            ::..:........|:....|..|..:|.|..||:..|||.|:|||||||||..:| |.|||:|.|
 Frog   403 ISPTSYLSPSLPALDWHLPSQSGPYELRIEVQPKSHHRAHYETEGSRGAVKASTG-GHPIVQLHG 466

  Fly   543 Y--DKVAVLQVFIGT-DIGRVAPHMFYQACKVAGKN-STQCNEKKVDGTMVIEIDFKPETDMTIT 603
            |  ::...:|:|||| |...:.||.|||..::.||. ||..:|..:..|.|:||...||.:|...
 Frog   467 YLENEPLTIQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHETIISNTKVLEIPLLPENNMRAI 531

  Fly   604 CDCVGILKERNVDVEHRFPE-HLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPP 667
            .||.||||.||.|:|.|..| .:.:||    ||.|:|||..:.:.:|.|.||||.||||.|:|..
 Frog   532 IDCAGILKLRNSDIELRKGETDIGRKN----TRVRLVFRVHIPQANGRTLTLQVASNPIECSQRS 592

  Fly   668 G--VPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTA 730
            .  :|.:.|:|.::.||.||.::.:.|.||..|:.|:|.|  .:.:|..
 Frog   593 AQELPLVEKQSTDNFPVIGGKKMILNGHNFHPDSKVIFVE--KAPDGHH---------------- 639

  Fly   731 ALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVS-SGKKSEPHTFTYTAKGQYTTL 794
             :||.....|||......|:..:||:.:|.|..||||...:.: ..|:|:...|||        |
 Frog   640 -VWEMEAKTDKEMFKPNTLVVEIPPFRNQRISSPVQVNFYVCNGKRKRSQYQIFTY--------L 695

  Fly   795 AAASTLSNTIHAQDVSGFMDTTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPIT 859
            .|...:..|....|.....  |....:.|.:                .:...:.....||||...
 Frog   696 PANVPIIKTEPTDDYESAQ--TCVPMSQGLT----------------QLSKPYYSQQIMMPPDPG 742

  Fly   860 TQIPMGVR--------RSSLPSVTPMITDQQLVHLNAVAASAEALKTELDDSNSHSPLTGESTPD 916
            :.:..|..        .||.|..:|.:.|......|...::....:..|..:....| |.:..|.
 Frog   743 SCLVSGFTSCQQRNTVMSSSPISSPKLHDLSASAYNKCISNPGHTQLGLQQTTGGVP-TIQEVPR 806

  Fly   917 S----PNAALQYHRFARKPSLDTIMYDQSNSLP-GFPTVVAPATAAAVAAAVDIDPTAVAVAVEL 976
            |    |::..|......:|.   :...||:|.| ||...|.|.:.::...::..:|:.:...  .
 Frog   807 SIVGHPSSPDQSSPIMLQPQ---VSLHQSSSCPLGFQQTVYPNSPSSPVPSITQEPSYLQPC--S 866

  Fly   977 AVKNEIVKHVVQQHQQMQE------------QMHEQQQQQQQQQQQQQQQQQQQPQQQQQQQVHK 1029
            ...:.::.....|||::|.            ::||.............:::.::..|.....|::
 Frog   867 PTHSAVIGQPQHQHQKVQRNESPNSQPLSLPELHEDSNHNLAPIPVTIKREPEELDQLYLDDVNE 931

  Fly  1030 FI-DELTKSTSVVS 1042
            .| ::|:.:.:|.|
 Frog   932 IIRNDLSSNNNVHS 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NFAT	NP_001096974.1	RHD-n_TonEBP	502..665	CDD:143642	79/167 (47%)
		IPT	669..787	CDD:301692	34/118 (29%)
nfatc1	XP_012820381.1	RHD-n_NFAT	417..591	CDD:143641	81/178 (46%)
		IPT	596..696	CDD:387656	34/126 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12533
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X749
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.100