Protein Alignment NFAT and nfatc3b

DIOPT Version :9

• Sequence 1: NP_001096974.1
• Gene: NFAT / 32321
• FlyBaseID: FBgn0030505
• Length: 1457
• Species: Drosophila melanogaster
• Sequence 2: XP_009296487.1
• Gene: nfatc3b / 566869
• ZFINID: ZDB-GENE-100922-25
• Length: 924
• Species: Danio rerio
• Alignment Length: 1020
• Identity: 233/1020 - (22%)
• Similarity: 371/1020 - (36%)
• Gaps: 314/1020 - (30%)

  Fly   142 PPPCDNSND-------------SGLGFDQHTELRSSAGAGGVTDPAANG-----GSGSNSGQRS- 187
            |.||.:.:.             |.:..|...||..:|....:..|..:.     .|..||.|.|
Zfish   133 PSPCSSLSSRSWLSDASSCESFSHIYDDVEAELNEAAAQVRLASPLVSPLPSPLPSPLNSPQASP 197

  Fly   188 --SLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQ--QQQQQQQQQQQQQQQQQQQH 248
              |.||:       ...:....||...:...::||:|||..|.  .|.....|..:....::...
Zfish   198 QVSPLVS-------PFGSPGCMAAYGDDPWYRYQQYHQQSLQYPFAQSLSPYQSPRTSITEETWL 255

  Fly   249 SPQQHLIRAIPVSRSRNNTKVMAHCLEDLDLISASSEDSSTIATPAGLDEDTGFVNDTKTTTTGG 313
            ||:.|                           |:||..||...:|.|...
Zfish   256 SPRPH---------------------------SSSSRPSSRPTSPCGKRR--------------- 278

  Fly   314 NSSSDPFGGVFQATEAAVAAAVNAFNLQQQQHSVQQQQHQ----LFQYNGLLLQ---PQQQLQQQ 371
            :||::...|:     |:...:.||......:.||.::...    ...|:.|.:.   |.:..:..
Zfish   279 HSSAEVIPGL-----ASPHLSPNATPSHSPRGSVTEESWMGGATFAPYHTLPVDVDVPSKTRRTY 338

  Fly   372 QSHHQQQQQQQQHHRHGKHIKRKKLECNQVELDNDDACSEDEFIRKIASSVTMSPTLE------- 429
            |::|.|.|              ..|...|     :|:..:|:.:.....:|:: |:|:
Zfish   339 QANHNQDQ--------------ASLFSGQ-----EDSGLQDQGLANSGIAVSL-PSLKKEDIVEH 383

  Fly   430 --ATPSP----PPIVASVAPATTIVSLLPLISSGNSNNNNNNNNIETKFISARNVTRVANKRQPT 488
              |.|:|    .|..||....:|   .||
Zfish   384 FLAVPTPFSWVKPKQASTLYRST---SLP------------------------------------ 409

  Fly   489 TPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGY-DKVAVLQVF 552
             ||:....|..||.:|::..||...|||.|:|||||||:|...|. .|:|:|.|| :|...||:|
Zfish   410 -PLDCPLPSQYGQCELKMEIQPRAHHRAHYETEGSRGAIKSECGR-HPVVKLIGYNEKPVSLQMF 472

  Fly   553 IGT-DIGRVAPHMFYQACKVAGKN-STQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNV 615
            ||: |...:.||.|||..::.||. :|...:..:..|.|:||...||.:|..:.||.||||.||.
Zfish   473 IGSADERYIRPHPFYQVHRITGKTVATPSQDTVISNTKVLEIPLLPENNMCASIDCAGILKLRNS 537

  Fly   616 DVEHRFPE-HLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQ--PPGVPEICKKSL 677
            |:|.|..| .:.:||    ||.|.|||..:.:.:|...:|||.|:||.|:|  ...:|::...|.
Zfish   538 DIELRKGETDIGRKN----TRVRAVFRVNIPQHNGKLLSLQVASSPIECSQRLAQELPQVESFSP 598

  Fly   678 NSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKE 742
            ......||.|:.|.|:|...::.|||.|     .|.|..|:              ||.:|.|..|
Zfish   599 ACGSASGGEEMRITGQNLNSESTVVFLE-----KGSDGKTQ--------------WEVNVRPLPE 644

  Fly   743 YLHQTHLICTVPPYLHQNILKPVQVQVSIVSSGKK----SEPHTFTYTA--KGQYTTLAAA---- 797
            ....|.::..:|||..:......|||. .|::||:    |:..||...|  |.:::|..||
Zfish   645 KSQNTSIVVKIPPYYKKTTASSTQVQF-YVTNGKRKRSGSQFFTFLSAAQVKQEFSTQPAAPSGQ 708

  Fly   798 -----------STLSNTIHAQDVSGFMDTTSASNASGSSGWSAAGGSGNNTSTGDNV--EAKHEI 849
                       .||..:.|.        :.|..:||..|....|..|.|:.:...::  .:..|.
Zfish   709 TELLEQWLLSEETLCASTHL--------SFSPQDASYLSRSHPADRSFNSRTDLHSMFPSSLIEF 765

  Fly   850 DSGMMPPPITTQIPMGVRRSSLPSVTPMITDQQLVHLNAVAASAEALKTELDDSNSHSPLTGEST 914
            :|.:...|  .|.|....:.|||...|                 |...|:||..
Zfish   766 NSSLYQKP--HQDPSYKAQPSLPVAFP-----------------EQTATQLDKG----------- 800

  Fly   915 PDSPNAALQYHRFARKPSLDTIMYD-------------QSNSLPGFPTV-VAPATAAAVAAAVDI 965
                      ::..|..:||.::.|             ||:|..|.||| ..|:|:.:.:.  :.
Zfish   801 ----------YQCIRSQNLDNLILDASGLHTMAAVSIPQSSSSQGLPTVSKVPSTSPSTSK--NA 853

  Fly   966 DPTAVAVAVELAVKNEIVKHVVQQHQQMQEQMHEQQQQQQQQQQQQQQQQQQQPQQQQQQQVHKF 1030
            :|.:.::.                         |..:|....:...:...:::|:::::
Zfish   854 EPASASLV-------------------------ESSEQYCVSENGDRLNIKEEPEEEKE------ 887

  Fly  1031 IDELTKSTSVVSSNGTTEPALFTTSAVIDHALTDILQAKVGIAPP 1075
            :|        ..|.|..:..|...|.:|...|.|..::..|.:.|
Zfish   888 LD--------FQSVGLQDITLDDVSEIIVRDLFDAPESGNGNSVP 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NFAT	NP_001096974.1	RHD-n_TonEBP	502..665	CDD:143642	71/166 (43%)
		IPT	669..787	CDD:301692	33/121 (27%)
nfatc3b	XP_009296487.1	RHD-n_NFAT	412..585	CDD:143641	74/177 (42%)
		IPT	590..689	CDD:301692	32/118 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28KEG
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X749
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910