Protein Alignment NFAT and NFATC4

DIOPT Version :10

• Sequence 1: NP_001096974.1
• Gene: NFAT / 32321
• FlyBaseID: FBgn0030505
• Length: 1457
• Species: Drosophila melanogaster
• Sequence 2: NP_001306972.1
• Gene: NFATC4 / 4776
• HGNCID: 7778
• Length: 965
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 116/304 - (38%)
• Similarity: 161/304 - (52%)
• Gaps: 33/304 - (10%)

  Fly   490 PLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGY-DKVAVLQVFI 553
            ||:....|...|::|.|..||...|||.|:|||||||||...| |.|:|:|.|| :|...||:||
Human   468 PLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPG-GHPVVKLLGYSEKPLTLQMFI 531

  Fly   554 GT-DIGRVAPHMFYQACKVAGKN-STQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNVD 616
            || |...:.||.|||..::.||. :|...|..|.||.|:|:...||.:|....||.||||.||.|
Human   532 GTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSD 596

  Fly   617 VEHRFPE-HLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPG--VPEICKKSLN 678
            :|.|..| .:.:||    ||.|:|||..:.:..|...::|..|.||.|:|...  :|::...|.:
Human   597 IELRKGETDIGRKN----TRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPS 657

  Fly   679 SCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEY 743
            :|.|.||.||.:.|.|||.|:.|||.|     .|.|...:              ||:....::..
Human   658 ACSVRGGEELVLTGSNFLPDSKVVFIE-----RGPDGKLQ--------------WEEEATVNRLQ 703

  Fly   744 LHQTHLICTVPPYLHQNILKPVQVQVSIVSSG--KKSEPHTFTY 785
            .::..|..|||.|.::.:.:||||.. .||:|  |:|...:|.:
Human   704 SNEVTLTLTVPEYSNKRVSRPVQVYF-YVSNGRRKRSPTQSFRF 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NFAT	NP_001096974.1	RHD-n_TonEBP	502..665	CDD:143642	75/166 (45%)
		IPT	669..787	CDD:472823	36/119 (30%)
NFATC4	NP_001306972.1	PHA03247	<277..476	CDD:223021	2/7 (29%)
		RHD-n_NFAT	470..643	CDD:143641	77/177 (44%)
		IPT_NFAT	648..748	CDD:238583	36/119 (30%)