| Sequence 1: | NP_001096974.1 | Gene: | NFAT / 32321 | FlyBaseID: | FBgn0030505 | Length: | 1457 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001265598.1 | Gene: | NFATC1 / 4772 | HGNCID: | 7775 | Length: | 943 | Species: | Homo sapiens |
| Alignment Length: | 1014 | Identity: | 233/1014 - (22%) |
|---|---|---|---|
| Similarity: | 352/1014 - (34%) | Gaps: | 293/1014 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 64 GGNNNTNFQAYQHHY---KSNFGMRMTMST-NSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITR 124
Fly 125 TGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFD----------QHTELRSSAGAGGVTDPAANGGS 179
Fly 180 ------GSN-------------SGQRSSLLVNSALTNTVA---AAAAAAAAAVASNTLQQHQQHH 222
Fly 223 QQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPV------SRSRNNTKVMAHCLEDLDLIS 281
Fly 282 ASSEDSSTIATPAGLDEDTGFVNDTKTTTTGGNSSSDP---------------------FGGVFQ 325
Fly 326 ATEAAVAAAVNAFNLQQQQH-----SVQQQQHQLFQYNGLLLQPQQQLQQQQSHHQQQQQQQQHH 385
Fly 386 RHGKHIKRKKLECNQVELDNDDACSEDEFIRKIASSVTMSPTLEATPSPPPIVASVAPATTIVSL 450
Fly 451 LPLISSGNSNNNNNNNNIETKFISARNVTRVANKRQPTTP-LNSVASSNDGQVQLEILSQPEQQH 514
Fly 515 RARYQTEGSRGAVKDRSGNGFPIVRLTGY--DKVAVLQVFIGT-DIGRVAPHMFYQACKVAGKN- 575
Fly 576 STQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNVDVEHRFPE-HLAQKNKKKSTRCRMV 639
Fly 640 FRTQLTRDDGTTETLQVCSNPIICTQPPG--VPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVV 702
Fly 703 FQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQV 767
Fly 768 QVSIVS-SGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQDVSGFMDTTSASNASGSSGWSAAG 831
Fly 832 GSGNNTSTGDNVEAKHEIDSGMMP------------PP-----ITTQIPMGVRRSSL----PSVT 875
Fly 876 PMITDQQLVHLNAVAASAEALKTELDDSNSHSP---------LTGESTPDSPNAALQYHRFARKP 931
Fly 932 SLDTIMYDQSNSLPGFPTVVAPATAAAVAAAVDIDPTAV 970 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NFAT | NP_001096974.1 | RHD-n_TonEBP | 502..665 | CDD:143642 | 79/167 (47%) |
| IPT | 669..787 | CDD:301692 | 33/118 (28%) | ||
| NFATC1 | NP_001265598.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 22..48 | 6/16 (38%) | |
| Calcineurin-binding | 118..123 | 1/4 (25%) | |||
| Trans-activation domain A (TAD-A) | 126..218 | 10/91 (11%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 200..298 | 16/110 (15%) | |||
| 3 X SP repeats | 203..298 | 15/107 (14%) | |||
| Nuclear localization signal | 265..267 | 0/1 (0%) | |||
| Nuclear export signal | 310..321 | 5/10 (50%) | |||
| RHD-n_NFAT | 416..590 | CDD:143641 | 81/178 (46%) | ||
| IPT | 595..695 | CDD:301692 | 33/126 (26%) | ||
| Nuclear localization signal | 682..684 | 0/1 (0%) | |||
| Trans-activation domain B (TAD-B) | 703..943 | 33/198 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 787..912 | 15/83 (18%) | |||
| Nuclear export signal | 924..933 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR12533 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X749 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.970 | |||||