Protein Alignment NFAT and nfatc2

DIOPT Version :9

• Sequence 1: NP_001096974.1
• Gene: NFAT / 32321
• FlyBaseID: FBgn0030505
• Length: 1457
• Species: Drosophila melanogaster
• Sequence 2: XP_002933215.2
• Gene: nfatc2 / 100490186
• XenbaseID: XB-GENE-492278
• Length: 900
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 173/612 - (28%)
• Similarity: 259/612 - (42%)
• Gaps: 166/612 - (27%)

  Fly   487 PTT---PLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGY--DKV 546
            |.|   ||.....:..|..:|:|..||:..|||.|:|||||||||..:| |.|:|:|.||  :|.
 Frog   363 PVTSLPPLEWPLPNQAGSYELQIEMQPKPHHRAHYETEGSRGAVKSPNG-GHPVVQLNGYMENKP 426

  Fly   547 AVLQVFIGTDIGRV-APHMFYQACKVAGKN-STQCNEKKVDGTMVIEIDFKPETDMTITCDCVGI 609
            ..||:||||...|: .||.|||..::.||. :|...||.|..|.|:|:..:|:|:|....||.||
 Frog   427 LGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEMPLEPKTNMRAIIDCAGI 491

  Fly   610 LKERNVDVEHRFPE-HLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPG--VPE 671
            ||.:|.|:|.|..| .:.:||    ||.|:|||..:...:|...:|||.||||.|:|...  :|.
 Frog   492 LKLKNADIELRKGETDIGRKN----TRVRLVFRVHIPEANGRIVSLQVASNPIECSQRSAHELPL 552

  Fly   672 ICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQE-TYDSVNGDDPATEIAVRQQLIGGTAALWEQ 735
            :.::.::||.|.||.::.:.|:||..::.|||.| |.|.             ||       :||.
 Frog   553 VERQDMHSCLVYGGQQMILSGQNFTAESKVVFTEKTSDG-------------QQ-------IWEM 597

  Fly   736 SVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVS-SGKKSEPHTFTY----TAKGQYTTLA 795
            ....||:....:.|...||.|..::|..||:|...::: ..|:|:...|||    :.|.:.....
 Frog   598 EATVDKDKSQPSMLFVEVPEYRSKHITSPVKVNFYVINGKRKRSQAQHFTYHPVPSIKTEPIDEY 662

  Fly   796 AASTLSNTIHAQDVSGFMDTTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPITT 860
            ::|.:.|.||                         ||.|   :......::|.:.:......:..
 Frog   663 SSSIVGNNIH-------------------------GGIG---TVPQAYFSQHSMANDAPSCLVAN 699

  Fly   861 QIPMGVRRSSLPSVTPMITDQQLVHLNAVAASAEALKTELDDSNSHSPLTGESTPDSPNAALQYH 925
            .:|....|:||||                                         |:|     :||
 Frog   700 LVPCQQTRASLPS-----------------------------------------PES-----RYH 718

  Fly   926 RFARKPSLDTIMYDQSNSLPGFPTVV----APATAAAVAAAVDIDPTA---VAVAVELAVKNEI- 982
            :  :.||  |:||.:|.||.  |:.:    :|..|:.:|.. |:.|.|   |.|.....|::.:
 Frog   719 Q--QNPS--TVMYQRSKSLS--PSQLGYHQSPLMASQIAIP-DVIPDAHRSVLVHAGSPVQSVLH 776

  Fly   983 ---------------VKHVVQQ--HQQMQEQM---HEQQQQQQQQQQQQQQQQQQQPQQ-----Q 1022
                           ..|.|::  ||..|..|   |......:..|.|..|.|:..|..     |
 Frog   777 SSANPQPSPVIHYSPTNHQVRRGSHQDFQHIMCSDHFATSPTRSSQPQVSQAQRMSPNPFPSVIQ 841

  Fly  1023 QQQQVHKFIDELTKSTSVVSSNGTTEP 1049
            ||           .::...|.||.:.|
 Frog   842 QQ-----------SNSPRASKNGPSGP 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NFAT	NP_001096974.1	RHD-n_TonEBP	502..665	CDD:143642	77/167 (46%)
		IPT	669..787	CDD:301692	34/123 (28%)
nfatc2	XP_002933215.2	RHD-n	371..545	CDD:385313	78/178 (44%)
		IPT_NFAT	550..650	CDD:238583	34/119 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12533
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X749
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100