DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango2 and Tango2

DIOPT Version :9

Sequence 1:	NP_001245654.1	Gene:	Tango2 / 32319	FlyBaseID:	FBgn0030503	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_038944430.1	Gene:	Tango2 / 360738	RGDID:	1310348	Length:	321	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	88/360 - (24%)
Similarity:	147/360 - (40%)	Gaps:	102/360 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCVIFFCADSNP-QPGGYKLILASNRDEFFARATLSAAKWANADHVYGGIDLEPGREGGTWLAIG 64
            ||:|||..|..| ....|:||||:||||.:.|.:..|..|.|...:..|:|:|.|:.|||||.|.
  Rat     1 MCIIFFKFDPRPVSKNAYRLILAANRDESYHRPSKLADFWENNSEILSGLDMEEGKAGGTWLGIS 65

  Fly    65 HSAGFFKVGALLNLTGEPKPRDAVAHKNILQPHNHNSNSTGINLCPKTTTSNSYRHPNPNPIQNP 129
            ...   |:|||               .|.|||.                             |.|
  Rat    66 TRG---KLGAL---------------TNYLQPR-----------------------------QEP 83

  Fly   130 NTNPSRGQSNNEHFLLGRGMIVADYVTRADEEHSILNYNERLLKDCTKYSAFNFVSIEI------ 188
            :..             |||.:|:.::|   .:...|:|.:::..:...|:.||.::.::
  Rat    84 DAR-------------GRGELVSHFLT---SDMDSLSYLKKVSTEGHLYNGFNLIAADLSTAKGD 132

  Fly   189 -----GSASQPARVKLLSNVPPTLEDFQNGEC------------------------YGFGNSLPH 224
                 |:..:|..: :|:...|.|...|..:|                        ||..|:|..
  Rat   133 VVCYYGNRGEPEPI-VLTPGEPALVSRQGRDCSYVGNTMCHLWPLHGQADLLPIGTYGLSNALLE 196

  Fly   225 SPFEKVRHGKQEFEAIVKAHGEASVETLSAQLMQLLRNKHKFWPDDELKTRAPNWGEGLSS--LN 287
            :|::|:..|||.|...|:.......:.|..||:::|.|:....||..::.:...:.:.:.|  ..
  Rat   197 TPWKKLCFGKQLFTEAVERSESLPKDILVTQLLEVLNNEEAQLPDPAIEDQGQEYIQPILSKYAA 261

  Fly   288 VHIEEHAYGSRTHSVVLVDSENKMHFIEETMTGLD 322
            |.:....||:||::::|||::..:.|.|.:|...|
  Rat   262 VCVRSATYGTRTNTIILVDADGHVTFTERSMLDKD 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango2	NP_001245654.1	TANGO2	1..318	CDD:283414	86/354 (24%)
Tango2	XP_038944430.1	TANGO2	1..294	CDD:399040	77/330 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335146
Domainoid	1	1.000	125	1.000	Domainoid score	I5355
eggNOG	1	0.900	-	-		E1_COG3332
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44029
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4602
OMA	1	1.010	-	-		QHG63496
OrthoDB	1	1.010	-	-		D1312210at2759
OrthoFinder	1	1.000	-	-		FOG0005228
OrthoInspector	1	1.000	-	-		oto97160
orthoMCL	1	0.900	-	-		OOG6_103320
Panther	1	1.100	-	-	LDO	PTHR17985
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4241
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770