Protein Alignment Tango2 and TANGO2

DIOPT Version :10

• Sequence 1: NP_001245654.1
• Gene: Tango2 / 32319
• FlyBaseID: FBgn0030503
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001309070.1
• Gene: TANGO2 / 128989
• HGNCID: 25439
• Length: 369
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 81/373 - (21%)
• Similarity: 132/373 - (35%)
• Gaps: 140/373 - (37%)

  Fly    15 GGYKLILASNRDEFFARATLSAAKWANADHVYGGIDLEPGREGGTWLAIGHSAGFFKVGALLNLT 79
            |.::||||:|||||::|.:..|..|.|.:.:..|:|:|.|:||||||.|...      |.|..||
Human    57 GSHRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGTWLGISTR------GKLAALT 115

  Fly    80 GEPKPRDAVAHKNILQPHNHNSNSTGINLCPKTTTSNSYRHPNPNPIQNPNTNPSRGQSNNEHFL 144
                        |.|||                                          ..:...
Human   116 ------------NYLQP------------------------------------------QLDWQA 126

  Fly   145 LGRGMIVADYVTRADEEHSILNYNERLLKDCTKYSAFNFVSIEI-----------GSASQPARVK 198
            .|||.:|..::|   .:...|:|.:::..:...|:.||.::.::           |:..:|..:.
Human   127 RGRGELVTHFLT---TDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIV 188

  Fly   199 LLSNVPPTLEDFQNGECYGFGNSLPHSPFEKVRHGKQEFEAIVKAHGEASVETLSAQLMQLLRNK 263
            |   .|.|         ||..|:|..:|:.|:..|||.|...|:.......:.|.|.|:.:|.|:
Human   189 L---TPGT---------YGLSNALLETPWRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNE 241

  Fly   264 HKFWPDDELK------------------TRAPNWGEGLSSL---------------------NVH 289
            ....||..::                  .|.|.:|....|.                     :.|
Human   242 EAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRYCSTVGAPPPIPCPTSHARGPAKKPSAH 306

  Fly   290 IEEHAYGS---------------RTHSVVLVDSENKMHFIEETMTGLD 322
            .:..|..|               .|::::|||::..:.|.|.:|...|
Human   307 SQSQASSSPEWIPELLPCPDAAAGTNTIILVDADGHVTFTERSMMDKD 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango2	NP_001245654.1	TANGO2	1..318	CDD:461729	79/367 (22%)
TANGO2	NP_001309070.1	TANGO2	60..352	CDD:461729	79/366 (22%)