DRSC/TRiP Functional Genomics Resources

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Protein Alignment tth and DPF1

DIOPT Version :10

Sequence 1:NP_572904.1 Gene:tth / 32318 FlyBaseID:FBgn0030502 Length:428 Species:Drosophila melanogaster
Sequence 2:XP_006723470.1 Gene:DPF1 / 8193 HGNCID:20225 Length:398 Species:Homo sapiens


Alignment Length:266 Identity:73/266 - (27%)
Similarity:103/266 - (38%) Gaps:101/266 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 IESFLKDVS---YRETIEYSANFNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQG 79
            |::.||.:.   |||.||:..::|.|||:||..||||||.|||||||:..::::|..|.||...|
Human     5 IQNPLKSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPG 69

  Fly    80 QIYTYPAARWRKSRRQYLSK-------MYSRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGS 137
            |||||||..|||.||..:.:       .|....|.|   |:||                    |.
Human    70 QIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAP---LKKE--------------------GG 111

  Fly   138 MPGSNSLASSSSLTLNMLTGGGAAPAVLGSLHSDTAHDFNGAFSLEESSSLGAAGGDTSDSKDSQ 202
            :|                    ..|.:...|.::|...   ...|:|..::          .|.|
Human   112 LP--------------------EGPVLEALLCAETGEK---KIELKEEETI----------MDCQ 143

  Fly   203 QQQHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPKSPADDEYDYDPRYGNKKRRKRRPGK 267
            :||..:..|                 |:::.|::             |..||     |:.|..||
Human   144 KQQLLEFPH-----------------DLEVEDLE-------------DDIPR-----RKNRAKGK 173

  Fly   268 RGGDSG 273
            ..|..|
Human   174 AYGIGG 179

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tthNP_572904.1 DPF1-3_N 24..89 CDD:464074 36/67 (54%)
DPF1XP_006723470.1 DPF1-3_N 13..79 CDD:464074 36/65 (55%)
SFP1 <186..220 CDD:227516
PHD1_DPF1 270..327 CDD:277160
PHD2_d4 328..383 CDD:277005
Blue background indicates that the domain is not in the aligned region.

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