DRSC/TRiP Functional Genomics Resources

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Protein Alignment tth and KAT6A

DIOPT Version :9

Sequence 1:NP_001285216.1 Gene:tth / 32318 FlyBaseID:FBgn0030502 Length:428 Species:Drosophila melanogaster
Sequence 2:XP_011542958.1 Gene:KAT6A / 7994 HGNCID:13013 Length:2048 Species:Homo sapiens


Alignment Length:343 Identity:69/343 - (20%)
Similarity:117/343 - (34%) Gaps:96/343 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 NLAKIESFLKDVSYRE--TIEYSANFNTRLCSER--------------RHRLPFLDPQTGVAQNH 62
            |:.|....:||....|  :.|...:.:|.:.||:              :..|..|..:..:.  |
Human  1399 NMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP--H 1461

  Fly    63 SQLFLDKRQRMPGFRQGQIYTYPAARWRKSRRQYLS-----KMYSRFPERPFQAL-----RKEHE 117
            |:|.|:..|.:....|.:...:..|  .:...:.|:     :.|::..|.|..::     ..||.
Human  1462 SELDLETVQAVQSLTQEESSEHEGA--YQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHN 1524

  Fly   118 ALVASGVNLGLSSLTSGVGSMPGSNSLASSSSLTLNMLTGG--GAAPAVLGSLHSDTAHDFNGAF 180
            :.::|            |.|.| |.|:.|.||..:..|..|  ..:|. .|||.:.:..      
Human  1525 SPISS------------VQSHP-SQSVRSVSSPNVPALESGYTQISPE-QGSLSAPSMQ------ 1569

  Fly   181 SLEESSSLGAAGGDTSDSKDSQQQQHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPKSPA 245
            ::|.|..:     |.....|          |.||.|            |...:|:.|:|......
Human  1570 NMETSPMM-----DVPSVSD----------HSQQVV------------DSGFSDLGSIESTTENY 1607

  Fly   246 DDEYDYDPRYGNKKRRKRRPGKRGGDSGGGGGGGGAGGGGNSGGSSSSRRRSAAARSRITTTDAA 310
            ::...||...|            |...|..........||.|  ||||..:|:..   :|...|:
Human  1608 ENPSSYDSTMG------------GSICGNSSSQSSCSYGGLS--SSSSLTQSSCV---VTQQMAS 1655

  Fly   311 LDASLEAIESGESVPGSN 328
            :.:|...::.....|.:|
Human  1656 MGSSCSMMQQSSVQPAAN 1673

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tthNP_001285216.1 Requiem_N 24..94 CDD:290758 15/85 (18%)
KAT6AXP_011542958.1 H15 85..162 CDD:197772
PHD1_MOZ_MORF 205..262 CDD:277090
PHD2_KAT6A_6B 264..310 CDD:277002
NAT_SF 549..823 CDD:302625
MOZ_SAS 609..787 CDD:280097
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156493
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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