Protein Alignment tth and Phf10

DIOPT Version :10

• Sequence 1: NP_572904.1
• Gene: tth / 32318
• FlyBaseID: FBgn0030502
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_077212.3
• Gene: Phf10 / 72057
• MGIID: 1919307
• Length: 497
• Species: Mus musculus
• Alignment Length: 205
• Identity: 46/205 - (22%)
• Similarity: 80/205 - (39%)
• Gaps: 48/205 - (23%)

  Fly    16 AKIESFLKDVSYRETIEYSANFNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQGQ 80
            :|:..::|..: ::..|:::|.|.....|||   .:.|.||.|.    |:...|.:.:|..|. :
Mouse   193 SKVPEYIKKAA-KKAAEFNSNLNRERMEERR---AYFDLQTHVI----QVPQGKYKVLPTDRT-K 248

  Fly    81 IYTYPAARWRKSRRQYLSKMYSRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGSMPGSNSLA 145
            :.:||.|......::|    |.|:.....:.| ..:.||....::..|.:|.|...|..|.:
Mouse   249 VSSYPVALIPGQFQEY----YKRYSPDELRYL-PLNTALYEPPLDPELPALDSDGDSDDGED--- 305

  Fly   146 SSSSLTLNMLTGGGAAPAVLGSLHSDTAHDFNGAFSLEESSSLGAAGGDTSDSKDSQQQQHQQHQ 210
                       |||           |......|.   .:|||...:.||:  ..|||:...
Mouse   306 -----------GGG-----------DEKRKNKGT---SDSSSGNVSEGDS--PPDSQEDTF---- 339

  Fly   211 HQQQAVKEEL 220
            |.:|..|:::
Mouse   340 HGRQKSKDKM 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tth	NP_572904.1	DPF1-3_N	24..89	CDD:464074	17/64 (27%)
Phf10	NP_077212.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..61
		WH_NTD_PHF10	72..160	CDD:411035
		SAY	88..294		26/114 (23%)
		Essential to induce neural progenitor proliferation	88..184
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..368		21/100 (21%)
		Essential to induce neural progenitor proliferation	291..333		15/71 (21%)
		PHD1_PHF10	379..432	CDD:277003
		PHD2_PHF10	434..477	CDD:277004