DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tth and enok

DIOPT Version :9

Sequence 1:NP_001285216.1 Gene:tth / 32318 FlyBaseID:FBgn0030502 Length:428 Species:Drosophila melanogaster
Sequence 2:NP_001286823.1 Gene:enok / 37859 FlyBaseID:FBgn0034975 Length:2291 Species:Drosophila melanogaster


Alignment Length:358 Identity:62/358 - (17%)
Similarity:113/358 - (31%) Gaps:124/358 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 FNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQGQIYTYPAARWRKSRRQYLSKMY 101
            :..:.||::....|.|     |.:::|::.::..:..|.:           ::..::||.:.|  
  Fly   287 YRCKTCSKQGFDTPKL-----VKKDNSRIKMEAERMTPSY-----------KYASNKRQSIKK-- 333

  Fly   102 SRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGSMPGSNSLASSSSLTLNMLTGGGA----AP 162
                                                   ..::.|.|:..|.:...|..    .|
  Fly   334 ---------------------------------------DGNIESPSTSKLCVYNDGNGQRRKVP 359

  Fly   163 AVLGSL---HSDTAHDF-----------NGAFSLEE---------SSSLGAAGGDTSDSKDSQQQ 204
            |.|.|.   ||:...:|           .|..:.:|         ||:..::..:..|.:|..:.
  Fly   360 ASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDRN 424

  Fly   205 QHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPK--SPADDEYDYDPRYGNKK---RRKR- 263
            ::.....|.::...:....       ..:|.||.|...  |..|||||.:..|...:   |.|. 
  Fly   425 RNGDDNDQDESTSSDSCTS-------SSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNV 482

  Fly   264 -RPGKRGGDSGGGGGGGGAG-----GGGNSGGSSSSRR------------------RSAAARSRI 304
             ..||:.......|.|.|:.     |..|.|.::.::.                  .|..|.|..
  Fly   483 FESGKQSCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFVKSKHNSNVKGIGYSKPAASTF 547

  Fly   305 TTTDAALDASLEAIESGESVPGSNGGPISSGGI 337
            .|:.|| :...::.....|.|..|..||  ||:
  Fly   548 ATSPAA-NRVQKSTPVASSTPEKNSAPI--GGM 577

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tthNP_001285216.1 Requiem_N 24..94 CDD:290758 7/56 (13%)
enokNP_001286823.1 H15 95..152 CDD:294056
PHD_SF 183..>215 CDD:304600
PHD 248..292 CDD:214584 0/4 (0%)
NAT_SF 713..989 CDD:302625
MOZ_SAS 768..947 CDD:280097
Ehrlichia_rpt <1150..>1539 CDD:118064
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45463868
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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