DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tth and Rsf1

DIOPT Version :9

Sequence 1:	NP_001285216.1	Gene:	tth / 32318	FlyBaseID:	FBgn0030502	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001074736.1	Gene:	Rsf1 / 233532	MGIID:	2682305	Length:	1441	Species:	Mus musculus

Alignment Length:	357	Identity:	72/357 - (20%)
Similarity:	115/357 - (32%)	Gaps:	110/357 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRM---------------PGFRQGQIYTYPAARWR 90
            ||.:...:|..||    ||....:....:::|:               |.|.:.|......|:..
Mouse   946 LCEKLEEQLQDLD----VALKKKERAERRKERLVYVGISIENIIPPQEPEFSEEQEEKKKDAKKS 1006

  Fly    91 KSR---------RQYLSKMYSRFPERPFQALRKEHEALVASGVNLG--LSSLTSGVGSMPGS--- 141
            |:.         |:.:|..:..|.|...:|:..:.:.....||..|  :|::|...|....:
Mouse  1007 KANALERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILD 1071

  Fly   142 -----------------------NSLASSSSLTLN------MLTGGGAAPAVLGSLHSDTAHDFN 177
                                   |.|.|.|:|...      .::.|.....|:.        |.|
Mouse  1072 EERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVS--------DEN 1128

  Fly   178 GAFSLEESSSLGAAGGDTSDSK--DSQQQQHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEE 240
            ...|.||..|     .:.||:.  ..:.::|.....:|........||:.:.||    |.:..|.
Mouse  1129 PDESEEEPPS-----NEDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDD----DEEEEES 1184

  Fly   241 PKSPADDEYDYDPRYGN-----KKRRKRRPGKR----GGDSGGGGGGGGAGGGGNSGGSSSSRRR 296
            .::..|.|.|:...:.:     ::||.||..||    ..||             .|.||..|.||
Mouse  1185 EENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDS-------------ESDGSQKSLRR 1236

  Fly   297 SAAARSRITTTDAALDASLEAIESGESVPGSN 328
            ....| |:.      ...|.:.||.||....|
Mouse  1237 GKEIR-RVH------KRRLSSSESEESFMSKN 1261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tth	NP_001285216.1	Requiem_N	24..94	CDD:290758	13/76 (17%)
Rsf1	NP_001074736.1	WHIM1	103..153	CDD:292246
		WHIM2	155..187	CDD:292247
		PHD_RSF1	896..941	CDD:277018
		BAH	918..>971	CDD:295389	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930