Protein Alignment tth and Dpf2

DIOPT Version :10

• Sequence 1: NP_572904.1
• Gene: tth / 32318
• FlyBaseID: FBgn0030502
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_001278007.1
• Gene: Dpf2 / 19708
• MGIID: 109529
• Length: 405
• Species: Mus musculus
• Alignment Length: 315
• Identity: 84/315 - (26%)
• Similarity: 122/315 - (38%)
• Gaps: 133/315 - (42%)

  Fly    14 NLAKIESFLKDVSYRETIEYSANFNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQ 78
            |:.|:   |.:..|::.:|...|:|.|||:||..||||||.||||||::..::::||.|.||...
Mouse     7 NVVKL---LGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLAS 68

  Fly    79 GQIYTYPAARWRKSRRQYLSKMYSRFPERP-----------FQALRKEHEALVASGVNLGLSSLT 132
            ||:|:|||.||||.||.:.       ||.|           .|.|:||
Mouse    69 GQLYSYPARRWRKKRRAHP-------PEDPRLSFPSIKPDTDQTLKKE----------------- 109

  Fly   133 SGVGSMPGSN--SLASSSSLTLNMLTGGGAAPAVLGSLHSDTAHDFNGAFSLEESSSLGAAGGDT 195
             |:.|..||:  :|..:..|...    |...|.|                   :..|||..  ..
Mouse   110 -GLISQDGSSLEALLRTDPLEKR----GAPDPRV-------------------DDDSLGEF--PV 148

  Fly   196 SDSKDSQQQQHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPKSPADDEYDYDPRYGNKKR 260
            |:|:                .::.::..:.|.||:|              |::|:.|    ..||
Mouse   149 SNSR----------------ARKRIIEPDDFLDDLD--------------DEDYEED----TPKR 179

  Fly   261 RKRRPGKRGGDSGGGGGGGGAGGGGNSGGSSSSRRRSAAARSRITTTDAALDASL 315
            |    ||               |...|.|.||:|::              ||||:
Mouse   180 R----GK---------------GKSKSKGVSSARKK--------------LDASI 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tth	NP_572904.1	DPF1-3_N	24..89	CDD:464074	32/64 (50%)
Dpf2	NP_001278007.1	DPF1-3_N	13..75	CDD:464074	29/61 (48%)
		SFP1	<201..247	CDD:227516	0/1 (0%)
		PHD1_DPF2_like	286..341	CDD:277161
		PHD2_d4	343..388	CDD:277005