DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tth and dpf3

DIOPT Version :9

Sequence 1:	NP_001285216.1	Gene:	tth / 32318	FlyBaseID:	FBgn0030502	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_012823348.1	Gene:	dpf3 / 100125167	XenbaseID:	XB-GENE-6067294	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	340	Identity:	98/340 - (28%)
Similarity:	132/340 - (38%)	Gaps:	106/340 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LKDVSYRETIEYSANFNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQGQIYTYPA 86
            |.|..|::.||:..::|:|||:||..||||||.|||||||:..::::||.|.||...||:|||||
Frog    12 LGDQFYKDAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGMAPGQLYTYPA 76

  Fly    87 ARWRKSRRQYLSKMYSRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGSMPGSNSLASSSSLT 151
            ..|||.||.:.       ||.|...|.:     :.|.|:..|..          .|.||..::|.
Frog    77 RCWRKKRRLHP-------PEDPRLRLLE-----IKSDVDFPLRK----------DNVLAEGTTLE 119

  Fly   152 LNMLTGGG----------AAPAVLGSLHSD-TAHDFNGAFSLEE------SSSLGAAGG-----D 194
            . :|.|.|          :...:...|.:| .|.|.||...:||      :.|.|.|.|     |
Frog   120 A-LLRGEGIEKKDVRDEESLQEIQRVLENDENADDANGEDDIEEEVPKRKNRSRGRARGGRRRND 183

  Fly   195 TS-DSKD-------SQQQQHQQ-------------------HQHQQQAVKEELLPKEWFYDDMDM 232
            || |..|       |.:|:|..                   |........||         ..|.
Frog   184 TSLDEHDKPYVCDNSYKQKHNSKTADKVCGKRYKNRPGLSYHYAHTHLADEE---------GTDC 239

  Fly   233 NDVDSLEEPKSPADDEYDYDPRYGNKKRRKRRPGKRGGDSGGGGGGGGAGGGGN----SGGSSSS 293
            .|.|: ..|.||:      ..|..|:|.||              |..||....|    ..|.||.
Frog   240 RDQDT-RSPSSPS------AIRNENQKPRK--------------GTDGAILSNNYCDFCLGDSSI 283

  Fly   294 RRRSAAARSRITTTD 308
            .::|......::..|
Frog   284 NKKSGQPEELVSCAD 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tth	NP_001285216.1	Requiem_N	24..94	CDD:290758	38/69 (55%)
dpf3	XP_012823348.1	Requiem_N	13..84	CDD:290758	38/70 (54%)
		PHD1_DPF3	273..329	CDD:277162	5/26 (19%)
		PHD2_d4	330..375	CDD:277005
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7328
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	1	1.000	-	-		FOG0001297
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X895
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010