DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ndc80 and AT3G54630

DIOPT Version :9

Sequence 1:	NP_572902.1	Gene:	Ndc80 / 32316	FlyBaseID:	FBgn0030500	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_191024.1	Gene:	AT3G54630 / 824628	AraportID:	AT3G54630	Length:	568	Species:	Arabidopsis thaliana

Alignment Length:	717	Identity:	151/717 - (21%)
Similarity:	273/717 - (38%)	Gaps:	237/717 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GTADKRQTRATKRSAATHTPSSSQAAPRRPSASRLPQPLNLERDRASQMGVTPKRGHRFVPSTAE 85
            |.|.||:|          |.....|.|        |.|.::|:.|           |.|....::
plant     4 GAAGKRRT----------TVGFGGAPP--------PPPPSIEQQR-----------HLFNSRDSD 39

  Fly    86 RAIA---PHS---DKKWVAERAQQILEYLH----------GIQNSEAPTGLIADLFSRPGGLRHM 134
            .:.|   |.|   ..:..::....::.:::          .|:.:..|:  :.|:..
plant    40 ASFASSRPSSIGLGGRGASDDRSSMIRFINAFLSTHNFPISIRGNPVPS--VKDISE-------- 94

  Fly   135 TIKQFVSILNFMFHHI-WRNRVTVGQNHVEDITSAMQKLQYPYQVNKSWLVSPTTQHSFGHVIVL 198
            |:|..:|.|::....| |.          ||:...::..:.|:::.||.|.:|.|.|::..|:.:
plant    95 TLKFLLSALDYPCDSIKWD----------EDLVFFLKSQKCPFKITKSSLKAPNTPHNWPTVLAV 149

  Fly   199 LDFLMD---FLPPLPS-SDVVEEEFPFMETMEQPSSYLNSMHCESTTIMSTTQAHAIQLDED-VN 258
            :.:|.:   |...|.| |..|.|:              |||:  ...|.|.  .|.|:.::| ||
plant   150 VHWLAELARFHQHLVSNSTSVPED--------------NSMN--FFAIQSF--GHFIRGEDDKVN 196

  Fly   259 GLLFEEASKCIALWDQELTNEEAKLQAETRD--QVISKKCDLPDRKALDQLIGDLKTKLQQLENK 321
            .|            |.:..   .||:||...  :.||         ..:::.|:|:.||:.|..
plant   197 DL------------DSQFL---GKLEAEKTSVAETIS---------GCEKISGELEAKLESLRK- 236

  Fly   322 LHDPSE-----------DNKLNKLERLTKEHDQLAQQLAASEEELIKKLKLYEQLSAQVEEKQSN 375
              .||:           :|.:||...:..|:......:....||..|:||      |:.||
plant   237 --GPSKKESLEKVKADLENDVNKFRTIVVEYTDRNPAMEKVVEEKAKELK------AKEEE---- 289

  Fly   376 LRQQMKYE-KRLEQAVNRQKFSAQQLKELQMKCDDMENYSKAYERQVKEV---------SELELH 430
             |:::..| |.|:::|..|.|||..:..::.:.       :|.||.|.:.         ...||:
plant   290 -RERISVENKELKKSVELQNFSAADVNRMRREL-------QAVERDVADAEVARDGWDQKAWELN 346

  Fly   431 QQVMLSRAKQKQLDSVEV-FNSHVRHLSMD-------------------------PVICGLIKSG 469
            .|:   |.:..|:.::.: .|..:|.|.:|                         |.:|.|. .|
plant   347 SQI---RNQFHQIQTLAIDCNQALRRLKLDIQFAVNERGETPAAVMGVDYKSVVKPALCSLC-DG 407

  Fly   470 IGQQSDLTLPLNPNQEDISERVQCLELLGKLLQQHRQQNIDRRQMLDKQVAKVKS-----DSIEL 529
            |...|             :|:|:  ||:  .||.|:.:          ..:|::|     .||:|
plant   408 IKGSS-------------AEKVE--ELV--TLQHHKSE----------MASKIESKRSLLGSIQL 445

  Fly   530 DTEIATMDSQLRAQKQRLTKMEA-SYRTKRDMQAQHRQQLLEDQYDQTARLDELEKREKQALEKL 593
              :|..::     :|.:|.|.|. ...||.|::|   :.|:|   ...|....||..||:|.|.:
plant   446 --QINDLE-----EKMKLVKKETQELSTKCDLEA---KTLVE---SVKAEALNLEVVEKEAAEFV 497

  Fly   594 EASKQRNEDLLTAAEQFQEQDLKARQDRLEKCEQKLAKAEDQLLAVESKVNATQAKLNEVEQKVY 658
            :||:.|    |..|.:..|::::|...:|......::|.::.:.:..|::....|.......::|
plant   498 KASELR----LQEAVKESEEEVQACAAQLFALIDSISKQKEYMDSKISEIKTGVADTASAVSEIY 558

  Fly   659 SA 660
            .|
plant   559 KA 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndc80	NP_572902.1	Ndc80_HEC	63..204	CDD:281754	26/157 (17%)
AT3G54630	NP_191024.1	Ndc80_HEC	28..171	CDD:397740	30/173 (17%)
AT3G54630	NP_191024.1	HEC1	78..544	CDD:227512	131/596 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925552at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910