Protein Alignment Ndc80 and ndc80

DIOPT Version :9

• Sequence 1: NP_572902.1
• Gene: Ndc80 / 32316
• FlyBaseID: FBgn0030500
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001011162.1
• Gene: ndc80 / 496580
• XenbaseID: XB-GENE-997352
• Length: 640
• Species: Xenopus tropicalis
• Alignment Length: 702
• Identity: 142/702 - (20%)
• Similarity: 271/702 - (38%)
• Gaps: 187/702 - (26%)

  Fly    48 RRPSASRLPQPLNLERDRASQMGVT-----------------PKRGHRFVPSTAERAIA------ 89
            ||.|.:.....|.|....|::||:|                 |..|      |:||..:
 Frog     2 RRSSVTNRQSLLPLRVQDANRMGLTTPQSKDRQGFGKLSMSKPHSG------TSERKTSFFGKRM 60

  Fly    90 -----------------------PHSDKKWVAERAQQILEYLHGIQNSEAPTGLIADLFSRPGGL 131
                                   |..||.::.:..:|:.|:|:  :|..:.|..:.       .|
 Frog    61 SNGTARTSQYGAFGGTEKIKDPRPLHDKAFIQQCIRQLCEFLN--ENGYSQTLTVK-------SL 116

  Fly   132 RHMTIKQFVSILNFMFHHIWRNRVTVGQNHVEDITSAMQKLQYPYQVNKSWLVSPTTQHSFGHVI 196
            :..:.|.|:.|..|::..|..|.........|:|....::|.||:.::||.:.:....|::..::
 Frog   117 QGPSTKDFLKIFAFIYTFICPNYENPESKFEEEIPRIFKELGYPFALSKSSMYTVGAPHTWPQIV 181

  Fly   197 VLLDFLMDFLPPLPSSDVVEEEFPFMETMEQPSSYLNSMHCESTTIMSTTQAHAIQLDEDVNGL- 260
            ..|.:|:|.   :....|:..|.|..|..:......|.:......:..|.:.:    |:.:.|.
 Frog   182 AALVWLIDC---VKLCCVLRSENPVFEEPQMGEQSENGIDFNQLFLDYTVRCY----DQFMEGRD 239

  Fly   261 LFEE--ASKCIALWDQELTNEEAKLQAETRDQVISKKCDLPDRKALDQLIGDLKTKLQQLENKLH 323
            .|||  |..||.| .:....:|:.|:|                             |||...:|
 Frog   240 TFEEYDADMCIRL-KEAYHVDESNLEA-----------------------------LQQESRRL- 273

  Fly   324 DPSEDNKLNKLERLTKEHDQLAQQLAASEEELIKKLKLYEQLSAQVEEKQSNLRQQMKYEKRLEQ 388
                   |.::|||.||.:....:||:     ::|||:  .|.|.:::.|:.|.:...:...|||
 Frog   274 -------LEEIERLEKEKENEPDRLAS-----MRKLKV--SLQADIQKYQNYLTEIESHSTLLEQ 324

  Fly   389 AVN---------RQKFSAQQLKELQMK-CDDMENYSKAYERQVK-EVSELELHQQVMLSRAKQKQ 442
            .|:         ..:..|.|.:.|::| ..|.:.||.|...::| |.:||   ||.:....|...
 Frog   325 RVSSVSEDLEATELESRAVQQENLRLKNILDNQKYSVADIERIKYEENEL---QQTIAKLTKDLD 386

  Fly   443 LDSVEVFNSHVRHLSMDPVICGLIKS--GIGQQSDLTLPLNPNQEDISERVQC-LELLGKLLQQH 504
            .|..::::..:::..|...:...:..  .||::..|..|..........::|| |:.....|..:
 Frog   387 EDKQQLWSEELKYAKMKESVETQLSEFHKIGRKVRLIPPTAEYANGYDFQIQCNLDSEQSSLIHY 451

  Fly   505 RQQ-NIDRRQMLDKQVAKVK---------SDSIE-LDTEIATMDSQLRAQKQRLTKMEASYRTKR 558
            |.: |:...::|.:...::.         .|.:| |:|.|....::::.||....|:|.:|:.|
 Frog   452 RNKINVPLVEILSQSEGQIAGATNKKMGVEDMVEQLNTLIGEKKNEVKVQKDEAQKLEETYQQK- 515

  Fly   559 DMQAQHRQQLLEDQYDQTARLDELEKREKQALEKLEASKQRNEDLLTAAEQFQEQDLKARQDRLE 623
                                ::|.|:.||:.:.::|:.::..:.|.:...:..::.||    .|:
 Frog   516 --------------------VEEAEEDEKRWISEIESLEKHRQLLESGVNKSLDEALK----DLQ 556

  Fly   624 KCEQKLAKAEDQLLAVESKVNATQAKLNEVEQKVYSAKLPSFQPVLDAIKNH 675
            |.:|:|...|.|          |:.::.:||.|:..        |:.|:.||
 Frog   557 KEQQELQLVEHQ----------TEEEMRQVENKLVR--------VVHAVANH 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndc80	NP_572902.1	Ndc80_HEC	63..204	CDD:281754	34/186 (18%)
ndc80	NP_001011162.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..79		14/82 (17%)
		HEC1	46..612	CDD:227512	132/658 (20%)
		Ndc80_HEC	50..205	CDD:367666	31/166 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I5173
OMA	1	1.010	-	-		QHG55244
OrthoDB	1	1.010	-	-		D364574at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.080