Protein Alignment CG11178 and AVL9

DIOPT Version :9

• Sequence 1: NP_572901.1
• Gene: CG11178 / 32315
• FlyBaseID: FBgn0030499
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_013215.1
• Gene: AVL9 / 850805
• SGDID: S000004104
• Length: 764
• Species: Saccharomyces cerevisiae
• Alignment Length: 719
• Identity: 167/719 - (23%)
• Similarity: 289/719 - (40%)
• Gaps: 190/719 - (26%)

  Fly    11 ILHILVVGFHHKLGCQVEFSHPPLISGSTGRNECPSGWKYLPTLALPDGSHNFAEDTVFFNLPSL 75
            |..|.:|.||||.|.::|:.:     |.....:....|..||..|||||||:|.|...:|.|  |
Yeast     9 IFGICLVDFHHKRGPEIEYWY-----GLPEGTQSAELWPNLPFQALPDGSHSFEETFTYFTL--L 66

  Fly    76 YEPAE--------------------SIYGVSCYRQIRVEKLKIRTADLTRSTVQKSVCILARLPI 120
            |:...                    :::.:||.|||:.::|..:..|:|||||||::.:::|.||
Yeast    67 YDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQIKSDELVTKDKDVTRSTVQKAIVVISRQPI 131

  Fly   121 YGYIEVKLALIADAFFDQGDFSGTELLAKAYQQLN------ACLQDDESRRPLRHFHVGLSLREI 179
            :|.|:.||:::.:|||.|.||...:::...|:.|.      :.:::.|:|     .::||.||:|
Yeast   132 FGQIKDKLSIVTNAFFLQHDFGDRKIIQSLYENLKSIYTPASLVRNAENR-----LYIGLCLRKI 191

  Fly   180 VLHWRHKTLMLFKLMLLQRRVVCFGSPVRQMCVLILGMASLVPRLLEKGFQEVACVRTSRPLSPM 244
            :..::...|:|.|.::|:::::.:|:.|..:|.|..|:.||:|.|:
Yeast   192 LHDFKRNALVLLKAIMLEKKIIVYGNDVEALCNLQFGLISLIPDLM------------------- 237

  Fly   245 PDFTDSLQREAQAEAEAELEAVASVAAATDEQKLTPESATAVEGEAEELALVSSAASAGEEQVSG 309
                                                                |:...:|..|:..
Yeast   238 ----------------------------------------------------SNLQDSGSPQLFQ 250

  Fly   310 DDTSTRSTPNSQSQDSSNGRNSSLTREASVDTLASNLAALCAVNPDEYRAPVSIFASGNLCLPYL 374
            |.:.....   .|..|||       ||:.:..|.               .|:.||..|.|..||.
Yeast   251 DISKLNVV---DSFKSSN-------RESVLRFLG---------------FPLPIFEKGGLFSPYT 290

  Fly   375 SLPYMDLLSDPMVLSYVIGTSNVLF-QQKRQLADVLVDIEAANLDAHDPELRRQLVLSTEDLRYM 438
            .|..|:.:.....|.::||:||.|. :||.:|..:.|:.:.:.:|..|..|...|.||:.|.:::
Yeast   291 PLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTVDILDKTLNPVLQLSSHDKKWI 355

  Fly   439 DYIMKHV---------QSPKEDA-EGSEYWIREQFQGYILALLRTAVAPDATP--KDNDH----- 486
            :.|...|         ::||... ||||.:||.||:.|:..||.:....|...  |:||.
Yeast   356 ESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFEDYLTGLLSSVKLSDYLDLHKENDQALKTI 420

  Fly   487 ------------FNAHFMGAFKRTQCFQEWYDVRPEPEFFEALPAGHPFAG--TLSVADMKL--- 534
                        ||.:::.::|.||.|. .::.|.:...|:..|..|.:.|  |||:...:.
Yeast   421 PEDMLNSNPVHLFNLNWVQSWKETQNFL-IFNSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLAT 484

  Fly   535 --KLAQTMQNSESGR-------------KINQAVNTTSRAVGGAISQAKGAFSSW--WSSITTAP 582
              .|.::..||.|.:             .|....:.:..:|....:..|.|.:.|  |......|
Yeast   485 FHNLKRSSSNSSSNKNGHQSEEDIKDQESIESKKSVSQISVNPGKNTDKPAANLWNSWKEYFNKP 549

  Fly   583 PNATNAGPATSSSNGQEGDVSEGAAAQEISVTFQNHKDVEDLDVAGVSIHLAGQEEAHESHESQS 647
            .|..|.....|:.:.:....:..|..:.:.....::|...:.|.....:   |..|.:|..::..
Yeast   550 KNTANEDVTESTEDLKNRSKTSNAIQKAMMGLGLHYKPDAETDQQSEEV---GNSEDNEDDDTDE 611

  Fly   648 VSCD 651
            .|.|
Yeast   612 DSED 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11178	NP_572901.1	Avl9	11..474	CDD:286833	127/499 (25%)
		Afi1	13..>70	CDD:285085	21/56 (38%)
		SPA	<368..417	CDD:285780	15/49 (31%)
AVL9	NP_013215.1	Avl9	9..401	CDD:401666	127/499 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346275
Domainoid	1	1.000	191	1.000	Domainoid score	I634
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I847
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56043
OrthoFinder	1	1.000	-	-		FOG0005854
OrthoInspector	1	1.000	-	-		oto100227
orthoMCL	1	0.900	-	-		OOG6_104063
Panther	1	1.100	-	-	LDO	PTHR31017
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R125
SonicParanoid	1	1.000	-	-		X4244
TreeFam	0	0.000	Not matched by this tool.
	11	11.020