Protein Alignment up and TNNT2

DIOPT Version :9

• Sequence 1: NP_001162742.1
• Gene: up / 32314
• FlyBaseID: FBgn0004169
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_001263274.1
• Gene: TNNT2 / 7139
• HGNCID: 11949
• Length: 298
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 94/293 - (32%)
• Similarity: 142/293 - (48%)
• Gaps: 63/293 - (21%)

  Fly     3 DDEEYTSSEEEEVVEETREETKPPQTPAEGEGD------------------PEFI--KRQDQKRS 47
            :||:..::||:...|...|||:..:...|.|..                  |..:  |..|.:|.
Human    31 EDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERV 95

  Fly    48 DLDD-----------QLKEYITEWRKQRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKEEEE 101
            |.||           :|:..|....:.|.|||:||..||::..:|:..|||:::   .|.:.|:|
Human    96 DFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQR---IRNEREKE 157

  Fly   102 RRVREAEEKKQREIEEKRMRLEEAEKKRQAMLQAMKDKDKKGPNFTIAKKDAGVLGLSSAAMERN 166
            |:.|.|||:.:||.||.|.:.|:..:|::|:...|        :|       |......|..||.
Human   158 RQNRLAEERARREEEENRRKAEDEARKKKALSNMM--------HF-------GGYIQKQAQTERK 207

  Fly   167 KTKEQLEEEKKIS-LSFRIKPLAIEGFGEAKLREKAQELWELIVKLETEKYDLEERQKRQDYDLK 230
            ..|.|.|.|||.. |:.|.|.|||:...|.:|||||:|||:.|..||.||:||:|:.|:|.|::.
Human   208 SGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEIN 272

  Fly   231 ELKER----QK-QQLRHKALKKGLDPEALTGKY 258
            .|:.|    || .:.|.||        .:||::
Human   273 VLRNRINDNQKVSKTRGKA--------KVTGRW 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
up	NP_001162742.1	Troponin	156..>233	CDD:395788	35/77 (45%)
TNNT2	NP_001263274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		13/63 (21%)
		Troponin	103..241	CDD:307228	50/155 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..219		39/116 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156938
Domainoid	1	1.000	50	1.000	Domainoid score	I11672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4736
Isobase	1	0.950	-	1	Normalized mean entropy	S6639
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41072
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11521
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.900