Protein Alignment up and TNNT1

DIOPT Version :9

• Sequence 1: NP_001162742.1
• Gene: up / 32314
• FlyBaseID: FBgn0004169
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_003274.3
• Gene: TNNT1 / 7138
• HGNCID: 11948
• Length: 278
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 96/301 - (31%)
• Similarity: 142/301 - (47%)
• Gaps: 67/301 - (22%)

  Fly     1 MSDDEEYTSSE---EEEVVEETREETKPPQTPAEGEGD---------PEFI--KRQDQKRSDLDD 51
            |||.||....|   |||..||..|..:.|:..||.|.:         |..|  |..:.:|.|.||
Human     1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65

  Fly    52 -----------QLKEYITEWRKQRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKEEEERRVR 105
                       :|:..|....:||.|||:||..|||:..:|:..|||:::   .|.::|.||:.:
Human    66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQR---FRTEKERERQAK 127

  Fly   106 EAEEKKQREIEEKRMRLEEAEKKRQAMLQAMKDKDKKGPNFTIAKKDAGVLGLSSAAMERNKTKE 170
            .||||.::|.||.:.|.|:..||::.:       ...|.:|      .|.|    ...|:.:.|.
Human   128 LAEEKMRKEEEEAKKRAEDDAKKKKVL-------SNMGAHF------GGYL----VKAEQKRGKR 175

  Fly   171 QLEEEKKIS-LSFRIKPLAIEGFGEAKL----------------REKAQELWELIVKLETEKYDL 218
            |...|.|:. ||.|.|||.|:..||.:|                |||||||.:.|.:||:||:||
Human   176 QTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240

  Fly   219 EERQKRQDYDLKELKERQKQQLRH-KALKKGLDPEALTGKY 258
            ..:.|:|.|::..|..|    :.| :..:||.....:.|::
Human   241 MAKLKQQKYEINVLYNR----ISHAQKFRKGAGKGRVGGRW 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
up	NP_001162742.1	Troponin	156..>233	CDD:395788	33/93 (35%)
TNNT1	NP_003274.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		20/61 (33%)
		Troponin	69..204	CDD:279349	49/154 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..153		19/50 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156937
Domainoid	1	1.000	50	1.000	Domainoid score	I11672
eggNOG	1	0.900	-	-		E1_KOG3634
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4736
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41072
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11521
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6876
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.880