DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment up and tnnt3

DIOPT Version :9

Sequence 1:	NP_001162742.1	Gene:	up / 32314	FlyBaseID:	FBgn0004169	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_012816190.1	Gene:	tnnt3 / 394748	XenbaseID:	XB-GENE-482605	Length:	277	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	81/243 - (33%)
Similarity:	138/243 - (56%)	Gaps:	30/243 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DDEEYTSSEEEEVVEETREETKPPQTPA----EGEG-DPEFIKRQDQKRSDLDDQLKEYITEWRK 62
            ::|.|..:||||..||..||...|:..|    |||. |.:.|:::.|.:..:  :|:..|....:
Frog    38 EEEAYGEAEEEEHGEEYDEEKPKPKLTAPKIPEGEKVDFDDIQKKRQNKDLI--ELQSLIDTHFE 100

  Fly    63 QRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKEEEERRVREAEEKKQREIEEKRMRLEEAEK 127
            .|.|||:||..|||:..||:..|:::::..|::.|   ||:.|.||||.:||.::...|.|:..|
Frog   101 ARKKEEEELIALKERIEKRRAERSDQQRIRAEKDK---ERQNRLAEEKARREEQDAIRRAEDDMK 162

  Fly   128 KRQAMLQAMKDKDKKGPNFT--IAKKDAGVLGLSSAAMERNKTKEQLEEEKKISLSFRIKPLAIE 190
            |::|:       ...|..::  :||.|          .:|.|.:...|::||| |:.|.|||.::
Frog   163 KKKAL-------SSMGATYSSYLAKAD----------QKRGKKQTAREQKKKI-LADRRKPLNVD 209

  Fly   191 GFGEAKLREKAQELWELIVKLETEKYDLEERQKRQDYDLKELKERQKQ 238
            ...:.||||||:|:|:.:.:||:||:::.|:.|:|.|::..|..|.::
Frog   210 HMNDDKLREKAKEMWDWLYQLESEKFEMGEKLKKQKYEITTLHRRVEE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
up	NP_001162742.1	Troponin	156..>233	CDD:395788	27/76 (36%)
tnnt3	XP_012816190.1	Troponin	82..218	CDD:366404	48/158 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4739
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48277
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050