Protein Alignment up and Tnnt3

DIOPT Version :9

• Sequence 1: NP_001162742.1
• Gene: up / 32314
• FlyBaseID: FBgn0004169
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_001157136.1
• Gene: Tnnt3 / 21957
• MGIID: 109550
• Length: 272
• Species: Mus musculus
• Alignment Length: 286
• Identity: 96/286 - (33%)
• Similarity: 143/286 - (50%)
• Gaps: 59/286 - (20%)

  Fly     1 MSDD-----EEYTSSEEEEVVEETREETKPP---QTPAEGEGDPEFIKRQDQKRS---------- 47
            |||:     ||....|||...||.:||...|   |..|..|.:.|..:.:::.|.
Mouse     1 MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEDAVAEEEREEDEEEEKPRPKLTAPKIPEG 65

  Fly    48 ---DLDD-----------QLKEYITEWRKQRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKE 98
               |.||           :|:..|....:.|.|||:||..|||:..||:..|||:::..|::
Mouse    66 EKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEK--- 127

  Fly    99 EEERRVREAEEKKQREIEEKRMRLEEAEKKRQAMLQAMKDKDKKGPNFT--IAKKDAGVLGLSSA 161
            |.||:.|.||||.:||.|:.:.|.|:..||::|:       ...|.|::  :||.|
Mouse   128 ERERQNRLAEEKARREEEDAKRRAEDDMKKKKAL-------SSMGANYSSYLAKAD--------- 176

  Fly   162 AMERNKTKEQLEEEKKISLSFRIKPLAIEGFGEAKLREKAQELWELIVKLETEKYDLEERQKRQD 226
             .:|.|.:...|.:||| |:.|.|||.|:...:.|||:||:|||:.:.:|||:|::..|:.|||.
Mouse   177 -QKRGKKQTAREMKKKI-LAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQK 239

  Fly   227 YDLKELKERQKQQLRHK----ALKKG 248
            ||:..|:.|..|..:|.    |..||
Mouse   240 YDITTLRSRIDQAQKHSKKAGATAKG 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
up	NP_001162742.1	Troponin	156..>233	CDD:395788	30/76 (39%)
Tnnt3	NP_001157136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		21/73 (29%)
		Troponin	76..211	CDD:366404	51/155 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..193		31/99 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	248..272		6/18 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847338
Domainoid	1	1.000	50	1.000	Domainoid score	I11585
eggNOG	1	0.900	-	-		E1_KOG3634
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4757
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43143
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11521
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6876
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.880