Protein Alignment Tpst and TPST1

DIOPT Version :10

• Sequence 1: NP_001259518.1
• Gene: Tpst / 32312
• FlyBaseID: FBgn0086674
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: XP_005250699.1
• Gene: TPST1 / 8460
• HGNCID: 12020
• Length: 376
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 206/336 - (61%)
• Similarity: 260/336 - (77%)
• Gaps: 3/336 - (0%)

  Fly    18 IIVITMFLFKFTELRPTCLFKVDAANE---LSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVP 79
            :::.::.:|...:....|..:::..::   |.|....|...|.....:.::|:::||||||||||
Human    14 LVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVP 78

  Fly    80 RSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCL 144
            ||||||||||||||||:|||:|||||||||.|:..|.:|.||.:||.|||:|.||::||:..|.|
Human    79 RSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLL 143

  Fly   145 EIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSY 209
            |||.|||||||.||||||..||..:|:..||||||||.|||||||:|||:|||||||.||||:||
Human   144 EIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSY 208

  Fly   210 RQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFIN 274
            |.|:.|||.|||.|:.||.::|..:||:|:|||||||||.|||.:||||.:|||.:||||||.|.
Human   209 RDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIG 273

  Fly   275 KPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKP 339
            |..||.|||||||:||||||||:.|:|||||:||.||::|||.|||||:.||||||||||:||||
Human   274 KAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 338

  Fly   340 DAWVQDNTSKL 350
            |..:.:||.::
Human   339 DPKIIENTRRV 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpst	NP_001259518.1	Sulfotransfer_3	73..264	CDD:463887	135/190 (71%)
TPST1	XP_005250699.1	Sulfotransfer_3	72..261	CDD:463887	133/188 (71%)