Protein Alignment Tpst and Tpst1

DIOPT Version :10

• Sequence 1: NP_001259518.1
• Gene: Tpst / 32312
• FlyBaseID: FBgn0086674
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_038865.1
• Gene: Tpst1 / 22021
• MGIID: 1298231
• Length: 370
• Species: Mus musculus
• Alignment Length: 336
• Identity: 204/336 - (60%)
• Similarity: 260/336 - (77%)
• Gaps: 3/336 - (0%)

  Fly    18 IIVITMFLFKFTELRPTCLFKVDAANE---LSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVP 79
            :::.::.:|...:....|..:::..::   |.:....|...|.....:.::|:::||||||||||
Mouse    14 LVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVP 78

  Fly    80 RSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCL 144
            ||||||||||||||||:|||:|||||||||.|:..|.:|.||.:||.|||:|.||::||:..|.|
Mouse    79 RSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLL 143

  Fly   145 EIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSY 209
            |:|.|||||||.||||||..||..:|:..||||||||.|||||||:|||:|||||||.||||:||
Mouse   144 EVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSY 208

  Fly   210 RQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFIN 274
            |.|:.|||.|||.|:.||.::|..:||:|:|||||||||.|||.:||||.:|||.:||||||.|.
Mouse   209 RDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIG 273

  Fly   275 KPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKP 339
            |..||.|||||||:||||||||:.|:|||||:||.||::|||.|||||:.||||||||||:||||
Mouse   274 KAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 338

  Fly   340 DAWVQDNTSKL 350
            |..:.:||.::
Mouse   339 DPKILENTRRV 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpst	NP_001259518.1	Sulfotransfer_3	73..264	CDD:463887	134/190 (71%)
Tpst1	NP_038865.1	Sulfotransfer_3	72..261	CDD:463887	132/188 (70%)
		Interaction with peptide substrate. /evidence=ECO:0000250|UniProtKB:O60507	102..106		3/3 (100%)