Protein Alignment Neto and Neto2

DIOPT Version :10

• Sequence 1: NP_001285211.1
• Gene: Neto / 32303
• FlyBaseID: FBgn0265416
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: XP_030099678.1
• Gene: Neto2 / 74513
• MGIID: 1921763
• Length: 560
• Species: Mus musculus
• Alignment Length: 495
• Identity: 137/495 - (27%)
• Similarity: 221/495 - (44%)
• Gaps: 86/495 - (17%)

  Fly   138 RCRLFVEGDPTKN--ELYSPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFL 200
            :|.::|.   |.|  ...||.||:.||.|..|..::.|...|.|.|.|...:.||....|:||.|
Mouse    79 QCGIWVR---TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDERYYIEPSFECRFDHL 140

  Fly   201 EIRDGQYGFSTLIGKFCGTDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYLDRSRDAPSTDL 265
            |||||.:|||.||.::||...|..|.|..|::|:.|.|||.:|..||.|.|.::      |..|.
Mouse   141 EIRDGPFGFSPLIDRYCGMKSPALIRSTGRFMWIKFSSDEELEGLGFRAKYSFI------PDPDF 199

  Fly   266 -----------NCTIDKGGFEGFINSTDVPAEIWEQVNRNK--IALDCIWRIQVKENWKIFLKFL 317
                       :|..:..|.:|.:.|:.|     ||..:.|  .|:||||.|:.....||:|:||
Mouse   200 TYLGGILNPIPDCQFELSGADGIVRSSQV-----EQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 259

  Fly   318 DFKLSKPNDCQTNFLDIFPEQTVMPLRVKNFCGSAGESITAESNILHLRFYADQTAINSTFGILF 382
            |:::...|:|:.||:.::...:.:......||.:....:..::.:..:|.:||:.:..|.|.:||
Mouse   260 DYQMEHSNECKRNFVAVYDGSSAIENLKAKFCSTVANDVMLKTGVGVIRMWADEGSRLSRFRMLF 324

  Fly   383 TAFRERGAACTEDEYDCEDATCISKDLKCNNLDNCKFRWDEEGC-TSEAAGQSE-----HVVIIV 441
            |:|.|  ..||...:.|....||:..|.||.:.||.:.|||..| ..:.||..|     |..||.
Mouse   325 TSFVE--PPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGLFEQITKTHGTIIG 387

  Fly   442 IVFGLILGGMVITFIVNC---IRKI-------------------------IRDQKIIREHIRESK 478
            |..|::|..::|:.:|..   .:|:                         :|:::|..:....|:
Mouse   388 ITSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLREKEISADLADLSE 452

  Fly   479 ESKLDEMGRNSKGRSR--------ENISRQKHSQTSLQILDDVSNRYYREAVPLSSQSSKADFKE 535
            |....:..|.|...||        ...|..|.|:|:|..::......:.:..|:.:.:|  .||:
Mouse   453 ELDNYQKLRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNS--TFKK 515

  Fly   536 KEHSILRRH-------ADMTQTSL-CGV---GEDDGESSS 564
            ..::..:.|       .|.....: |.:   |.||...:|
Mouse   516 SSYTFKQAHECPEQALEDRVMEEIPCEIYVRGRDDSAQAS 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	44/100 (44%)
		CUB	<298..384	CDD:238001	24/85 (28%)
		LDLa	392..426	CDD:238060	13/33 (39%)
Neto2	XP_030099678.1	CUB	80..193	CDD:238001	49/115 (43%)
		CUB	<240..326	CDD:238001	24/85 (28%)
		LDLa	332..366	CDD:238060	13/33 (39%)