DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Neto and cdcp2

DIOPT Version :9

Sequence 1:	NP_001285211.1	Gene:	Neto / 32303	FlyBaseID:	FBgn0265416	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_021324134.1	Gene:	cdcp2 / 567759	ZFINID:	ZDB-GENE-070705-485	Length:	544	Species:	Danio rerio

Alignment Length:	534	Identity:	121/534 - (22%)
Similarity:	188/534 - (35%)	Gaps:	138/534 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 RSERQAEEDQVDRCRLFVEG-------DPTKNELYSPEYPNLYPKNINCTRVITAPKGQIIRLDF 183
            :..||..|... |.|.|..|       ..:...:.||.:|.|||.:.:||.:|...:|..:.|.|
Zfish    18 QGRRQGSESGF-RQRYFCLGVKCGGILSASSGNVSSPNFPGLYPYDTDCTWLIVVSEGSSVLLTF 81

  Fly   184 RNSFNIEAKEGCKFDFLEIRDG-QYGFSTLIGKFCGTDFPPEITSKERYLWLHFHSDETIEYTGF 247
            .: |.:|....|.:|:::|.:| ......|:|||||...||:.:|....:.:.||||..:...||
Zfish    82 HH-FELEYHTDCAYDYIKIYNGISEDEGNLLGKFCGDVSPPQFSSSWNVMSIIFHSDRHVARKGF 145

  Fly   248 SAVYEYLDRSRDAPSTDLNCTIDKGGFEGFINSTDVPAEIWEQVNRNKIALDCIWRIQVKENWKI 312
            ...|.          .|: |.....|..|.|.|...|    :..:.|   .:|.|.:||.....:
Zfish   146 LVGYR----------KDM-CGGVLTGLSGVIASPGYP----QDYSNN---AECSWTVQVSNQSLV 192

  Fly   313 FLKFLDFKLSKPNDCQTNFLDIFPEQTVMPLRVKNFCGS--AGESITAESNILHLRFYADQTAIN 375
            .|.||||:|.....|..:::.:|...||....:.|:||:  ...:||..:.:|        ....
Zfish   193 SLVFLDFQLENNEGCNFDYVALFDGPTVKHHHLGNYCGNEQPPNTITTSNQLL--------VVFK 249

  Fly   376 STFGI---LFTAFRERGAACTEDEYDCEDATCISKDLKCN-----------NLDNCKFRWDEEGC 426
            |.|.|   .|.|:...|        :|:.   ..||:..|           |..||  .|    .
Zfish   250 SDFNIGGRGFKAYYFSG--------ECQQ---FLKDISGNFTSPHYPNIYPNNINC--HW----T 297

  Fly   427 TSEAAGQSEHVVIIVIVFGLILGGMVITFIVNCIRKIIRD-----QKIIREHIRESKESKLDEMG 486
            .:.|||   :.|.:...|..:.....:|.:.:.....:.|     ..::.:.....:...|...|
Zfish   298 ITLAAG---YRVKLFFPFLELEDRNSLTSMCDYDSVAVYDGDSEADSVLGQWCGSEQPPSLTSRG 359

  Fly   487 ----------RN--SKGRSRE-------NISRQKHSQTSLQILDDVSNRYYREAVPLSSQSSKAD 532
                      ||  .||.:..       |||..: ::..:||......:..||.|.|.:.|..|.
Zfish   360 NKLLVVLNTDRNFAFKGFTASYLGVVPVNISCTR-TEFQIQISRQALPQLERENVYLGNPSCSAQ 423

  Fly   533 FKEKEHSILRRHADMTQTSLCGVGEDDGESSSTTTATHEMMTKAAMSAVPSNACDMGCQTRE--S 595
            ..|..:.||.|..:                                       |....|.|:  :
Zfish   424 LTETSYKILGRFVN---------------------------------------CGTAAQKRQNIT 449

  Fly   596 LFVNSPGIGPSAGP 609
            :.|||..|..|.||
Zfish   450 MLVNSLYIDVSDGP 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	33/101 (33%)
		CUB	<298..384	CDD:238001	24/90 (27%)
		LDLa	392..426	CDD:238060	8/44 (18%)
cdcp2	XP_021324134.1	CUB	39..145	CDD:278839	31/106 (29%)
		CUB	154..265	CDD:238001	32/125 (26%)
		CUB	276..381	CDD:238001	18/113 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910