DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Neto and Cdcp2

DIOPT Version :9

Sequence 1:	NP_001285211.1	Gene:	Neto / 32303	FlyBaseID:	FBgn0265416	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_038967409.1	Gene:	Cdcp2 / 298306	RGDID:	1563467	Length:	566	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	71/254 - (27%)
Similarity:	111/254 - (43%)	Gaps:	52/254 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 SPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFLEIRDG-QYGFSTLIGKFC 217
            ||.:|:|||.|..|:.:|...:|..:.|.| ::|::|..:.|.||||||.:| ......|:|:||
  Rat    69 SPNFPSLYPYNTECSWLIVVAEGSSVLLTF-HTFDLEYHDTCGFDFLEIYNGASRDKGNLLGRFC 132

  Fly   218 GTDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYLDRSRDAPSTDLNCTIDKGGFEGFINSTD 282
            |...||..||....:.:.||||:.:...||||.|:     :|.      |.....|..|.::|.:
  Rat   133 GQAPPPPFTSSWHVMSVVFHSDKHVASRGFSAGYQ-----KDV------CGGVLTGLSGILSSPE 186

  Fly   283 VPAEIWEQVNRNKIALDCIWRIQVKENWKIFLKFLDFKLSKPNDCQTNFLDIFPEQTVM----PL 343
            .|       |.....::|.|.|:......:.|.|:||::....:|      ::...||:    |.
  Rat   187 YP-------NNYPNNVECHWLIRASGPATVKLVFVDFQVEGSEEC------MYDHVTVLGAPGPA 238

  Fly   344 RVKNFCGSAGESITAESNILHLRFYADQTAINSTFGI----------------LFTAFR 386
            ...::|||     |....::.|. :..|....|.|.|                :|||.|
  Rat   239 HGHHYCGS-----TRPPTLVSLG-HELQVVFKSDFNIGGRGFKAHYFSGECQEVFTAVR 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	39/98 (40%)
		CUB	<298..384	CDD:238001	21/105 (20%)
		LDLa	392..426	CDD:238060
Cdcp2	XP_038967409.1	CUB	56..167	CDD:238001	39/98 (40%)
		CUB	171..280	CDD:238001	26/127 (20%)
		CUB	283..396	CDD:238001	4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000