DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Neto and mfrp

DIOPT Version :9

Sequence 1:	NP_001285211.1	Gene:	Neto / 32303	FlyBaseID:	FBgn0265416	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_009289590.1	Gene:	mfrp / 101885305	ZFINID:	ZDB-GENE-160728-150	Length:	572	Species:	Danio rerio

Alignment Length:	312	Identity:	78/312 - (25%)
Similarity:	135/312 - (43%)	Gaps:	50/312 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LYSPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFLEIRDGQYGFSTLIGKF 216
            |.||.:|.:||.:.:|..||......::::.. :|..||....|.||:||:|: :...::...:|
Zfish   149 LSSPNHPGVYPPDSHCVWVIRVSPPSLVQIQV-SSLAIEGPSPCLFDWLEVRE-ETEKTSAATRF 211

  Fly   217 CGTDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYL-----DRSRDA---------------- 260
            ||...||.:.:....:.:.||||.:|..|||.|.|..:     ..||:.
Zfish   212 CGNVAPPTLNTNSSTVLVSFHSDGSIGGTGFIAQYHSILPGQRSCSREEFMCDSGHCLLPVFICD 276

  Fly   261 -------PSTDLNCT----IDKG---GFEGFINSTDVPAEIWEQVNRNKIALDCIWRIQVKENWK 311
                   .|.:|||:    :..|   |..|.::|.:.|.....|..       |.|:|.|::...
Zfish   277 GQPNCQDHSDELNCSHKHRVCGGQITGEYGSLSSPNHPKPYPHQQM-------CTWQISVEDGQV 334

  Fly   312 IFLKFLDFKLSKPNDCQTNFLDIFP-EQTVMPLRVKNFCGSA-GESITAESNILHLRFYADQTAI 374
            |.|.|.:|.|...:.|:.::::::. .:|.:    ..:|||| ...:|:...:|.:.|.||:...
Zfish   335 IRLSFQNFSLEAQDVCKFDYVEVYDGAETAL----GRYCGSALPPDLTSSGPVLTVVFVADEGVA 395

  Fly   375 NSTFGILFTAFRERGAACTEDEYDCEDATCISKDLKCNNLDNCKFRWDEEGC 426
            :|.|...|.|.......|:..::.|....|:.:|..|:...:|....||..|
Zfish   396 DSGFYASFQAISLSERTCSPAQFACPTGECLHQDWLCDGWSDCADGADEHHC 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	32/99 (32%)
		CUB	<298..384	CDD:238001	23/87 (26%)
		LDLa	392..426	CDD:238060	8/33 (24%)
mfrp	XP_009289590.1	CUB	138..248	CDD:238001	33/100 (33%)
		LDLa	256..290	CDD:238060	4/33 (12%)
		CUB	297..405	CDD:238001	29/118 (25%)
		LDLa	413..447	CDD:238060	8/33 (24%)
		Fz	459..563	CDD:279700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910