DRSC/TRiP Functional Genomics Resources

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Protein Alignment Neto and cubn

DIOPT Version :9

Sequence 1:NP_001285211.1 Gene:Neto / 32303 FlyBaseID:FBgn0265416 Length:822 Species:Drosophila melanogaster
Sequence 2:XP_021326049.1 Gene:cubn / 100144772 ZFINID:ZDB-GENE-060228-6 Length:3626 Species:Danio rerio


Alignment Length:573 Identity:126/573 - (21%)
Similarity:189/573 - (32%) Gaps:198/573 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 RGSTCSAQQPQQ-RPHKQQQQQQQQNQRLIPGQRCSLLM---LLIVGQAVYASAGSEIIANRSAS 64
            ||...|.|.||. :|:.....|..    :.||.|.|:..   ..:.|.....|.| :.:..|:..
Zfish  2116 RGVLSSPQYPQNYKPNLNCNWQVM----VTPGFRVSVTFQSPFQVQGYGNQCSTG-DYLELRNGP 2175

  Fly    65 AGESLIMLSNFTVATPPPAPRFTSPFREQD-------VAEGEELAGGGQVDWLDEQHPLTISRPP 122
            .|.|..:......:..|      |.|:..|       |::|.....|.::  |.|.|.       
Zfish  2176 DGNSPTLSGRLCGSNVP------STFQTTDNSLYAHFVSDGSNEGNGFKL--LFEAHS------- 2225

  Fly   123 RAGRSERQAEEDQVDRCRLFVE---GDPTKNELYSPEYPNLYPKNINCTRVITAPKGQIIRLDFR 184
                          ..|...:|   ||| ...:.||:||:.||:||:|..:||.|.|:.::|||.
Zfish  2226 --------------SACGGLIELNDGDP-PGYITSPDYPSNYPQNIDCVWIITVPNGEAVQLDFE 2275

  Fly   185 NSFNIEAKEGCKFDFLEIRDGQYGFSTLIGKFCGTDFPPEITSKERYLWLHFHSDETIEYTGFSA 249
            ..|.||...||.||::|||||....:.|||:.||...|....|....::|.|.:|.::.:.||.|
Zfish  2276 GDFYIEPHSGCLFDYIEIRDGPTSDADLIGRLCGNTRPSTQHSSGTTMYLRFRTDASVTHIGFKA 2340

  Fly   250 VY------------------------EYLDRSR-----DAPS--------------TDLNCTID- 270
            .|                        .|.|.|.     :.|:              :..||..| 
Zfish  2341 KYSIAVCGGTYIGQNGVIRSPGFPGSNYPDNSNCEWYLEGPTGHYLTLTYTAFDLQSSANCNSDY 2405

  Fly   271 -------------------------------------------KGGFE----------------- 275
                                                       .|||.                 
Zfish  2406 VEIREYNASGRLLGKHCGNNLPAPMDTGDSFAYVKFVSDASANAGGFSLSFEASIEECGGDLNAP 2470

  Fly   276 -GFINSTDVPAEIWEQVNRNKIALDCIWRIQVKENWKIFLKFLDFKLSKPNDCQTNFLDIFPEQT 339
             |.|:|.:.|       |....:..|.|.|.|.:..::.|...|.:|...:.|..:|::|....|
Zfish  2471 FGTISSPNYP-------NLYPHSRICRWSITVPQGRRVTLTINDLRLEDQSTCAFDFVEILNGLT 2528

  Fly   340 VMPLRVKNFCGS--AGESITAESNILHLRFYADQTAINSTFGILFTAFRERGAACTEDEYDCEDA 402
            ....|:...||:  ||..:.:..|.:.:.|..|.:..|..|              |.|....|.|
Zfish  2529 PSAPRLDRLCGTVPAGTQVKSSGNTMTVIFSTDSSVSNGGF--------------TADYSSEESA 2579

  Fly   403 TC----------ISKDL----KCNNLDNCKFRWDEEGCTSEAAGQSEHVVIIV 441
            .|          .|.|.    ..||| ||::.......|:.:      :|:|:
Zfish  2580 VCGGILNEPGNFTSPDFGNGNYSNNL-NCEWLIQNPHHTNSS------IVVII 2625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NetoNP_001285211.1 CUB 151..252 CDD:238001 42/124 (34%)
CUB <298..384 CDD:238001 21/87 (24%)
LDLa 392..426 CDD:238060 12/47 (26%)
cubnXP_021326049.1 EGF_CA 133..164 CDD:238011
EGF_CA 167..208 CDD:238011
EGF_CA 260..299 CDD:311536
EGF_3 308..346 CDD:315598
EGF_3 352..387 CDD:315598
EGF_CA 397..430 CDD:238011
EGF_CA 433..469 CDD:238011
CUB 475..588 CDD:238001
CUB 593..704 CDD:238001
CUB 711..820 CDD:278839
CUB 824..932 CDD:238001
CUB 939..1049 CDD:278839
CUB 1058..1166 CDD:278839
CUB 1174..1285 CDD:238001
CUB 1287..1399 CDD:238001
CUB 1403..1515 CDD:238001
CUB 1522..1632 CDD:238001
CUB 1635..1750 CDD:238001
CUB 1755..1865 CDD:238001
CUB 1869..1979 CDD:238001
CUB 1994..2105 CDD:238001
CUB 2108..2223 CDD:238001 26/119 (22%)
CUB 2228..2344 CDD:238001 47/116 (41%)
CUB 2347..2458 CDD:238001 10/110 (9%)
CUB 2463..2575 CDD:238001 28/132 (21%)
CUB 2581..2694 CDD:238001 11/52 (21%)
CUB 2697..2808 CDD:238001
CUB 2813..2926 CDD:238001
CUB 2928..3038 CDD:238001
CUB 3041..3152 CDD:238001
CUB 3161..3274 CDD:278839
CUB 3281..3395 CDD:238001
CUB 3399..3509 CDD:238001
CUB 3514..3626 CDD:238001
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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