Protein Alignment Set2 and ATX1

DIOPT Version :10

• Sequence 1: NP_572888.2
• Gene: Set2 / 32301
• FlyBaseID: FBgn0030486
• Length: 2362
• Species: Drosophila melanogaster
• Sequence 2: NP_850170.1
• Gene: ATX1 / 817721
• AraportID: AT2G31650
• Length: 1062
• Species: Arabidopsis thaliana
• Alignment Length: 950
• Identity: 168/950 - (17%)
• Similarity: 289/950 - (30%)
• Gaps: 350/950 - (36%)

  Fly   742 PEKPVAETVSKKEKAMENPARSSPAIVDK--------KVRAGEMEKKVVKSTKGTVPEKKMDSKK 798
            |...|.|::..:.|.:.|......:::.:        :::.    |:.:...||.:....:..|:
plant   316 PAVIVDESIIGERKGLNNKVSGGGSLLVQFFGTHDFARIKV----KQAISFIKGLLSPSHLKCKQ 376

  Fly   799 SCAAVTPAKQKESGKSAKEAILK------KETEKEKSSAKLDSSSPNTLDKKG------KDTAQW 851
                    .:.|.|....:..||      :.::.:|.:..:||...|:.::..      .|...|
plant   377 --------PRFEEGMQEAKMYLKAHRLPERMSQLQKGADSVDSDMANSTEEGNSGGDLLNDGEVW 433

  Fly   852 SPQLQTLPKSSTKPPQ---------ESAPSVISKTTSNQPAPKEEQHAAKKGLSDNSPPSVLKAK 907
                       .:|.:         :.....:.|..::....|:|.|...:|.:         |.
plant   434 -----------LRPTEHVDFRHIIGDLLIINLGKVVTDSQFFKDENHIWPEGYT---------AM 478

  Fly   908 EKAVSGFVECDAMFKAMDLANAQLRLDEKNKKKLKKVPTKVEAPPKVEPPTAVPVPGQKKSLSGK 972
            .|..|                    |.:.:...|.|:....:|..|..|...|.....::.....
plant   479 RKFTS--------------------LTDHSASALYKMEVLRDAETKTHPLFIVTADSGEQFKGPT 523

  Fly   973 TSLRRNTVYEDSPNLERNSSPSSDSAQANTSA----GKLKPSKVKKKINPRRSTICEAAKDLRSS 1033
            .|...|.:|.....::.:.||:....:.|.|.    |...|..:|            ..:||
plant   524 PSACWNKIYNRIKKVQNSDSPNILGEELNGSGTDMFGLSNPEVIK------------LVQDL--- 573

  Fly  1034 SSSSTPTREVAASSPVSTSSDSSSKRNGS-------KRTTSDLDGGSKLDQRRYTICE-DRQPET 1090
             |.|.|      ||.||...:|..:....       :....|||        :..:|. |.:.|.
plant   574 -SKSRP------SSHVSMCKNSLGRHQNQPTGYRPVRVDWKDLD--------KCNVCHMDEEYEN 623

  Fly  1091 AIPVPLTKRRFSMHPK--ASANPLHDTLLQTAGKKRGRKEGKESLSRQNSLDSSSSASQGAPKKK 1153
            .:.:...|.|..:|.|  ....|....|...            :|.|..:.|        .|.:.
plant   624 NLFLQCDKCRMMVHAKCYGELEPCDGALWLC------------NLCRPGAPD--------MPPRC 668

  Fly  1154 ALKSAEILSAALLETESSESTSSGSKMSRWDVQTSPELEAA-----NPFGDIAKFIE-DGVNLLK 1212
            .|  ..::..|:      :.|:.|    ||     ..|..|     ....|:.|... ||||.:.
plant   669 CL--CPVVGGAM------KPTTDG----RW-----AHLACAIWIPETCLSDVKKMEPIDGVNKVS 716

  Fly  1213 RDK----------------------------------------VDEDQRKEGQDEVKREADP--- 1234
            :|:                                        ::.|...||:     |||.
plant   717 KDRWKLMCTICGVSYGACIQCSNNSCRVAYHPLCARAAGLCVELENDMSVEGE-----EADQCIR 776

  Fly  1235 -----------------EEDEFAQRVANMETPATTPTPSPT---------------QSNPEDSAS 1267
                             .||..  :.|..:|....|.|:|:               :..||..|:
plant   777 MLSFCKRHRQTSTACLGSEDRI--KSATHKTSEYLPPPNPSGCARTEPYNCFGRRGRKEPEALAA 839

  Fly  1268 TTTVLKELET-----GGGVRRSHRIKQKPQGPRASQGRGVASVALAPISMDEQLAELANIEAINE 1327
            .::....:|.     ||..|......:...|.:.||....:::    :||.|:
plant   840 ASSKRLFVENQPYVIGGYSRLEFSTYKSIHGSKVSQMNTPSNI----LSMAEK------------ 888

  Fly  1328 QFLRSEGLNTFQLLKENFYRCARQVSQENAEMQCDCFLTGDEEAQGHLSCGAGCINRMLMIECGP 1392
                              ||..|:..::                  .|:.|...|:
plant   889 ------------------YRYMRETYRK------------------RLAFGKSGIH--------- 908

  Fly  1393 LCSNGARCTNKRFQQHQCWPCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHL- 1456
                                         |.||.|:|....|:.::||.||::.....::|:.|
plant   909 -----------------------------GFGIFAKLPHRAGDMMIEYTGELVRPSIADKREQLI 944

  Fly  1457 YSKDRNRHYYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGE 1521
            |:.......|...:..|.|||||..|:|:..|||||.||..::..||||:..|..|:.:.|...|
plant   945 YNSMVGAGTYMFRIDDERVIDATRTGSIAHLINHSCVPNCYSRVITVNGDEHIIIFAKRHIPKWE 1009

  Fly  1522 EITFDYQYLRYGRDAQRCYCEAANCRGWIGGEPDSDEGEQ 1561
            |:|:||::...| :...|.|....|||.:.   |::..||
plant  1010 ELTYDYRFFSIG-ERLSCSCGFPGCRGVVN---DTEAEEQ 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	valS	<709..832	CDD:237855	14/103 (14%)
		AWS	1358..1410	CDD:197795	3/51 (6%)
		SET_SETD2	1410..1551	CDD:380949	47/141 (33%)
		WW	2014..2043	CDD:459800
		SRI	2266..2355	CDD:462404
ATX1	NP_850170.1	Tudor_Agenet_AtEML-like	207..257	CDD:410475
		PWWP_AtATX1-like	300..396	CDD:438970	13/91 (14%)
		FYRN	447..497	CDD:461787	11/78 (14%)
		FYRC	508..597	CDD:470645	21/110 (19%)
		PHD_ATX1_2_like	611..657	CDD:276969	9/57 (16%)
		ePHD_ATX1_2_like	668..784	CDD:277132	21/137 (15%)
		SET_SETD1-like	885..1034	CDD:380916	52/235 (22%)