|
Fly 19 GRGRPPKVALSALGNTPPHINPSLKHADAEASPTAPEDQDSGQSECRRSSRKKIIKFDVRDLLNK 83
|..|..|.||||...|...........|||......|.|...|.:..: :.|
Human 3203 GAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQ--------------IRK 3253
Fly 84 NRKAHKIQIE-ARIDSNPSTGHSQSGTTAASTSMSTATASAASASSAATVSRLFSMFEMSHQSLP 147
.:|.|...|| .||. ..|....|..|.| .|:.
Human 3254 QQKEHAELIEDYRIK------QQQQCAMAPPTMM---------------------------PSVQ 3285
Fly 148 PPPP------PPTALEIFAKPRPTQSLIVAQVTSEPSAV---GGAHPVQTMAGLPPVTPRKRGRP 203
|.|| ||| ..:||..::..|:..:.... |...||: |..||...| ...|
Human 3286 PQPPLIPGATPPT------MSQPTFPMVPQQLQHQQHTTVISGHTSPVR-MPSLPGWQP--NSAP 3341
Fly 204 RKSQLADAAIIPTVI---VPSCSDSDTNSTSTTTSNMSSDSGELP------------GFPIQKPK 253
....|....|.|.:. :.:|:.: ..|.||.:..||..| .|..::.|
Human 3342 AHLPLNPPRIQPPIAQLPIKTCTPA-----PGTVSNANPQSGPPPRVEFDDNNPFSESFQERERK 3401
Fly 254 SKLRVSLKRLKLGGRLESSDSGNSPSSSSPEVEPPALQDENAMDERPKQEQNLSRMVDAEENSD- 317
.:||...:|.:: ....||: .:.|:.:|.:.||: .||.:|.:|.
Human 3402 ERLREQQERQRI--------------QLMQEVD-----RQRALQQRMEMEQH--GMVGSEISSSR 3445
Fly 318 -SDSQIIF----IEIETESPKG------EEEQEEGRPVEVE---------PQDLIDIDMELAKQE 362
|.|||.| :..:...|.| :.:|:.|:.::.: |.....:.....:|.
Human 3446 TSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQV 3510
Fly 363 PTPDPEEDLDEIMVEVLSGPPSLWSADDEAEEEEDATVQRA------TP--PGKEPAADSCSSAP 419
..|....|...|.| |.|:..|...........:.|:: || |...|.|: ||.|
Human 3511 GPPSFVPDSPSIPV----GSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVAN--SSLP 3569
Fly 420 RRSRRSAPLSGSSRQGKT--LEETFAEIAAE---SSKQILEAEESQDQEEQHILIDLIEDTLSES 479
..:.|....|.|..|.| |.:.:::|..| ..|:..:.:...|.|... ..:...|
Human 3570 -CGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTK------APSTPHS 3627
Fly 480 EVTSSVSPTIEHMVVEEVVVEENQLVDEADEILDSKQEFVIKKVFSESDNIAASLNKDIFEPKVE 544
::|:..:|.|........|...::|..:|| ||.| ||
Human 3628 DITAPPTPGISETTSTPAVSTPSELPQQAD------QESV--------------------EP--- 3663
Fly 545 TKATCGEVVPRPEMVTEDVYITEGIAATLEKSAVVTKPTTEMIAETKLSDEVVIEPPLKDESDP- 608
..|:|..:|..:|..|:..:.|..|.|..
Human 3664 -----------------------------------VGPSTPNMAAGQLCTELENKLPNSDFSQAT 3693
Fly 609 --KQTEVELPESKPAVNIP-KSERILSAEVETTSSPLVPPECCTLESVSGPVLLETSLSTEEKSN 670
:||.......|.::..| |:|.|...:.||.|.| ....|.| ||::.
Human 3694 PNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCP----------GQEEPKL-------EEQNG 3741
Fly 671 ENVETTPLKTEAAKEDSPP---AAPEEEASNSSEEPNFLLEDYES----NQEQ----VAEDEMMK 724
..||...:....:...||| .||..:..:.:|....||::.:| ||:. .:||:..|
Human 3742 SKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTK 3806
Fly 725 CNNQKGQKQTP--------------------LPEMKEPEKPVAETVSKKEKAMENPARSSPAIVD 769
:|:..:||.| ||:.....:...:...:.::..|..|..|
Human 3807 -DNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRS----- 3865
Fly 770 KKVRAGEMEKKVVKSTKGTVPEKKMDSKKSCAAVTPAK----------QKESGKSAKEAILKKET 824
||.:..|.||:.:.|:..|....|..:..|.....||. ||.:...| |
Human 3866 KKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFA--------T 3922
Fly 825 EKE---KSSAKLDSSSPNTLDKK-------------GKDTAQWSPQLQTLPKSSTKPPQESAPSV 873
.:| |:...:......||..| .:..|| .|:...:|.|...||.
Human 3923 TEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQ-GPKTVDVPASLPTPPH------ 3980
Fly 874 ISKTTSNQPAPKEEQHAAKKGLSDNSPPSVLKAKEKAVSGFVECDAMFKAMDLANAQLRLDEKNK 938
:||...:.:.|...:...|:..|| :..::|.| || :.:..||:..:
Human 3981 -----NNQEELRIQDHCGDRDTPDSFVPS---SSPESVVG-VE---VSRYPDLSLVK-------- 4025
Fly 939 KKLKKVPTKVEAPPKVEPPTAVPVPGQKKSLSGKTS-LRRN-------TVYEDSPNLERNSSPSS 995
|.||:..|...:|: ..|.:||:| .||| |:|..|| ...||:.
Human 4026 ----------EEPPEPVPSPIIPI---LPSTAGKSSESRRNDIKTEPGTLYFASP---FGPSPNG 4074
Fly 996 DSAQANTSAGKLKPSKVKKKINPRRSTICEAAKDL---RSSSSSSTPTREVAASSPVSTSSDSSS 1057
..:...:.|..|.|:..: ..|::..|..|| |..:| .||:::..|.:....||
Human 4075 PRSGLISVAITLHPTAAE-----NISSVVAAFSDLLHVRIPNS-----YEVSSAPDVPSMGLVSS 4129
Fly 1058 KRNGSKRTTSDLDGGSKLDQRRYTICEDRQPETA---------------IPVPLTKRRFSMHPKA 1107
.| ::.| |:.|::.:.....|.:| :|.|.|....|.:..:
Human 4130 HR---------INPG--LEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDS 4183
Fly 1108 SANPLHDTLLQT------------AGKKRG-------RKEGKESLSRQNS-----------LDSS 1142
|........|:. :|.::. .|:.:||..|... |.||
Human 4184 SHGIAESAALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSS 4248
Fly 1143 SSASQGAPKKKALKSAEILSAALLETESSESTSSGSKMSRWDVQTSPEL-EAANPFGD------- 1199
::.::.:..|:::.| :..:.:.||.|.......:.:|..||...|:| |.|:|...
Human 4249 TAQAKNSENKESIPS--LPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPP 4311
Fly 1200 -------IAKFIEDGVNLLKRDKVD------EDQR-----------KEGQDEV-------KREAD 1233
.||..|..|.:..:.::. ||.| |:....: |...:
Human 4312 AFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCE 4376
Fly 1234 PEEDEFAQRVANMETPATTP----------------TPSPTQSNPED--------SASTTTVLKE 1274
.|.|||.:::.....|...| |..|.:....| .|..:|.:.|
Human 4377 DEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYE 4441
Fly 1275 LETG-----------------------GGVRRSHRIK---------------------------Q 1289
.:.| |.....||.: .
Human 4442 TQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMH 4506
Fly 1290 KPQGPRASQGRGVASVALAPISMDE--QLAELANIEAINEQFLRSEGLNTF-----------QLL 1341
||:|....:....|......:..|| |:|.:.. |.|..:|| |||
Human 4507 KPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQ---------RGERDHTFRVGSLIFHTIGQLL 4562
Fly 1342 KENF-------------YRCARQV-SQENAEMQCDCFLTGDEE------------AQGH------ 1374
.:.. |..:|.. |...|..:|. :|...|| .|||
Human 4563 PQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCR-YLCSIEEKDGRPVFVIRIVEQGHEDLVLS 4626
Fly 1375 ---------------------------------------LSCGA------------GCIN----- 1383
|:..| .|.|
Human 4627 DISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRY 4691
Fly 1384 -RMLMIECGPLCSNGARC-------------------------TNKRFQ---------------- 1406
|..::|. ||..|...| |:|.||
Human 4692 GRNPLMEL-PLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFV 4755
Fly 1407 -----QHQC----WPCRVF--RTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKD 1460
|::. |...|: |:..:|.|:.|...|.....::||:|.:|.:|...|::.|| :.
Human 4756 HSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLY-ES 4819
Fly 1461 RNRHYYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGEEITF 1525
:||..|...:..:.|||||..|..:|||||||.||...:..|.....:|...|.:.||.|||:.:
Human 4820 QNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCY 4884
Fly 1526 DYQYLRYGRDAQR--CYCEAANCRGWI 1550
||:: .:..|..: |:|.|.|||.|:
Human 4885 DYKF-DFEDDQHKIPCHCGAVNCRKWM 4910
| 
