DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set2 and setmar

DIOPT Version :9

Sequence 1:	NP_572888.2	Gene:	Set2 / 32301	FlyBaseID:	FBgn0030486	Length:	2362	Species:	Drosophila melanogaster
Sequence 2:	NP_001107072.1	Gene:	setmar / 564575	ZFINID:	ZDB-GENE-080204-61	Length:	293	Species:	Danio rerio

Alignment Length:	320	Identity:	89/320 - (27%)
Similarity:	126/320 - (39%)	Gaps:	78/320 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1319 LANIEAINEQFLRSEGLNTFQLLKENFY--------------RCARQVSQENAEMQCDCFLTG-- 1367
            |.|:..:.|..:..|.|:.||.:.||..              .|:.:| |.....:|.|...|
Zfish    12 LENVPVLIENSVPKEALSYFQYVPENVQGPGCDLDPNAVTLPGCSCRV-QSCFPERCPCLRFGQT 75

  Fly  1368 -DEEAQGHLSCGAGCINR--------MLMIECGPLCSNGARCTNKRFQQHQCWPCRVFRTEKKGC 1423
             |..|         |:|:        ..:.||...||.|..|..:..|...|....||.|..:|.
Zfish    76 YDSRA---------CLNQHPQDATYSRPVFECNAFCSCGESCQTRVVQNGVCVRLGVFSTADRGL 131

  Fly  1424 GITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDRNRHYYFMALR--------GEAVIDATS 1480
            |:.|...:|.|.|:.||.||||..:|..|||  .|:......|.:|::        .:..:|..:
Zfish   132 GVEALERLPCGRFVCEYAGEVIGIDEARRRQ--LSQTPLHMNYIIAVQEHKGLDRVTQTFVDPVN 194

  Fly  1481 KGNISRYINHSCDPNAETQKWTVNGEL-RIGFFSVKPIQPGEEITFDYQYLRYGRDAQRCYCEAA 1544
            .||:.|:|||||.||.......|:..| |:..|:.:.|:..||:||||.
Zfish   195 LGNVGRFINHSCQPNLIMLPVRVHSVLPRLALFANRDIECYEELTFDYS---------------- 243

  Fly  1545 NCRGWIGGEPDSDEGEQLDEESDSDAEMDEEELEAEPEEGQPRKSAKAKAKSKLKAKLPL 1604
                  ||:..|.|..:||||:...|  |.||:        |:|.......|.....|||
Zfish   244 ------GGQNSSAETAKLDEETHVGA--DGEEI--------PQKKVCRCGASNCSGFLPL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	AWS	1358..1410	CDD:197795	14/62 (23%)
		SET	1414..1533	CDD:214614	44/127 (35%)
		PostSET	1535..1551	CDD:214703	0/15 (0%)
		WW	2014..2043	CDD:278809
		SRI	2270..2348	CDD:285448
setmar	NP_001107072.1	Pre-SET	8..111	CDD:282838	25/108 (23%)
setmar	NP_001107072.1	SET	119..243	CDD:214614	43/125 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840