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Protein Alignment Set2 and setdb1a

DIOPT Version :9

Sequence 1:	NP_572888.2	Gene:	Set2 / 32301	FlyBaseID:	FBgn0030486	Length:	2362	Species:	Drosophila melanogaster
Sequence 2:	NP_001038232.1	Gene:	setdb1a / 553292	ZFINID:	ZDB-GENE-030131-2421	Length:	1436	Species:	Danio rerio

Alignment Length:	1651	Identity:	313/1651 - (18%)
Similarity:	511/1651 - (30%)	Gaps:	621/1651 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 RPKQEQNLSRMVDAEENSDSDSQIIFIEIETESPKGEEEQEEGRPVEVEPQDLIDIDMELAKQEP 363
            |.|.::||.||     ..|...:.|..|:| .:|...:.:|:...||           |..||:
Zfish     3 REKDDENLLRM-----TKDDLQRWIQAEVE-RNPHLMQRREQLAQVE-----------EWVKQK- 49

  Fly   364 TPDPEEDLD----------EIMVE---VLSGPPSLWSAD--DEAEEEEDATVQRATPPGKEPAAD 413
                |.|..          |.::|   |:.|..:|...|  ||..|||
Zfish    50 ----ERDSTCTRLLYSNACESVLECESVMKGLYALLGLDYRDEDSEEE----------------- 93

  Fly   414 SCSSAPRRSRRSAPLSGSSRQGKTLEETFAEIAAESSKQILEAEESQDQEEQHILIDLIEDTLSE 478
                           .|..:....::  .|:..||....::...|..|.::. ::|||
Zfish    94 ---------------GGGGQPHDVIQ--IADDEAERRGNVICNGEDDDNDDL-VVIDL------- 133

  Fly   479 SEVTSSVSPTIEHMVVEEVVVEENQLVDEADEILDSKQEFVIKKVFSESDNIAASLNKDIFEPKV 543
                .:...|:|.| :|:|.|    .:.::.:::....:.|.|.....:..::.| :.||..|
Zfish   134 ----GATKETLEPM-LEKVTV----AIQKSSKLVQDLVQMVSKTSMGATSPLSTS-SSDINRP-- 186

  Fly   544 ETKATCGEVVPRPEMVTEDVYITEGIAATLEKSAVVTKPTTEMIAETKLSDEVV-----IEPPLK 603
             :.::..|:| |||.||..:.||..|.....:|.......:.:...::....:.     .:|.:|
Zfish   187 -SSSSTPEIV-RPESVTPKLEITNSITIVKTESLSSVPKISSLFNSSEQCKSIADHDSYFKPTIK 249

  Fly   604 DESDPKQTEV---ELPESKPAVNIPKSERILSAEVETTSSPLVP---PECCTLESVSGPVLLETS 662
            .|  |:.|.:   |..||.|...:.|:|   |...:.|.|.:.|   ||..:.:|.:
Zfish   250 TE--PEWTPLTPWEDSESSPFEKLIKTE---SQSTDVTPSVMTPNKQPELLSFQSTT-------- 301

  Fly   663 LSTEEKSNENVETTPLKTEAAKE-DSPPAAPEEEASNSSEEPNFLLEDYES-------NQEQ--- 716
                     .::..|..|:|..| .|||       |||.     |||::.|       |:.|
Zfish   302 ---------KIKPEPQSTQANTELSSPP-------SNSK-----LLENHNSLSIAAIKNESQLKA 345

  Fly   717 -VAEDEMMKCNNQKGQKQTPLPEMKEPEKPVAETVSKKEKAM--ENPARSSPAIVDKKVRAGEME 778
             |:|.::::.:::    |:.....|...||...|.|.|.|:.  .|.|.:|....|.|||.
Zfish   346 SVSEVDLLESDSE----QSDNAATKTRFKPSEVTASSKLKSSGDHNSASASLNRTDPKVRP---- 402

  Fly   779 KKVVKSTKGTVPEKK----MDSKKS---------CAAVTPAKQKESGKSAKEAILKKETEKEKSS 830
                .:..||.|..|    :|:..|         ....||.::.....:.|||::..:.|....:
Zfish   403 ----VTPSGTPPPSKSPPAVDNTASVETNQTDSELPTETPVEESTLPSNPKEAVIMSDAESTDKT 463

  Fly   831 AKLDSSSPNTLDKKGKDTAQWSPQLQTLPKSSTKPPQESAPSVISKTTSNQ--------PAPKEE 887
            .|     |.|..|..|      |.:.|....|.....:|.|  ::||:|.|        |:...:
Zfish   464 EK-----PQTRKKSSK------PSVTTTSPESRLTSSKSPP--VTKTSSTQKETARAQSPSDSID 515

  Fly   888 QHAAKKGLSD---NSP-PSVLKAKEKAVSGFVECDAMFKAMDLANAQLRLDEKNKKKLKKVPTKV 948
            :.|..:...|   ||| .|..|..:|....    ||..|......:......::.|.||::..||
Zfish   516 ESADMEDSPDEPSNSPTESPTKTPDKTTRN----DAPAKPSKAKKSSKHSSSESSKTLKEIKLKV 576

  Fly   949 EAPPKVEPPTAVPVPGQKKSLSGKTSLRRNTVYEDSPN-------------LERN---------- 990
            .|          .|.|:|:.........:....||..|             |..|
Zfish   577 GA----------AVLGKKRHNHWSRGTVQEVETEDDGNTYKVEFKKGKTIVLSANHVAAYKPPSL 631

  Fly   991 ----------SSPSSDSAQANTSAGKLKPSKVKKK----------------INPRRSTICEAAKD 1029
                      :|..|::.::..:||.:.....:|.                ..|....:|:..|.
Zfish   632 KDLYIGCRVVASAKSENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKK 696

  Fly  1030 LRSSSSSSTPTREV-----AASSPVST----SSDSSSKRNGSKRTTSDLDGGSKLDQRRYTIC-- 1083
            :.......:..::|     ...:|::.    ..::.:.|||.....:.|    :||.....||
Zfish   697 VWREIKDESSRKQVKDYLQVYPNPIAVVLRLGQETKAVRNGQFEDCTVL----QLDGSLVQICYK 757

  Fly  1084 EDRQPETAIP-------VPLTKRRFSMHPKASANPLHDTLLQTAGKKRGRKEGKESLSRQNSLDS 1141
            .|:|.|....       :...|.|...|               :.||....|||...|:..:|.|
Zfish   758 NDKQKEWIYKGSDKLEHILTIKNRHKQH---------------SHKKHHSPEGKTQSSQPKTLHS 807

  Fly  1142 SSSAS-----------------------QGAPKKKALKSAEILSAA------LLETESSESTSSG 1177
            |.|||                       |....|.::...:|:|.|      |.:.....|.|..
Zfish   808 SKSASTSTSSANVSPVSSDSVSPARVTRQSDKTKTSISPQKIMSPAFQPKVVLQKISLPSSISPA 872

  Fly  1178 SKMSRWDVQTSPELEAANPFGDIAK---FIEDGVNLLKRDKVDEDQRKEGQ----------DEVK 1229
            :::|..:..:| .:.|..|..|..:   |.||.|.:|     :::|.|...          :||:
Zfish   873 ARVSNSNTNSS-LISAKRPAPDEEEDEYFSEDEVEVL-----EQEQNKSVYLHQRCCPACLEEVR 931

  Fly  1230 -READ----------PEEDEFAQRVAN-------------------------------------- 1245
             .:.|          |...:|.:..|.
Zfish   932 PHQVDIHHGKNPLLIPLLFKFRRMTARRRIDGKLFFHIFYRSPCGRSLCDMQEVQDYLFETRCDF 996

  Fly  1246 --METPATTPTPSPTQSNPEDSASTTTVLKELETGGGVRRSHRIKQKPQGPRASQGRGVASVALA 1308
              :|.....|.....::.|   .||||....|..                |..|:|:.|..|...
Zfish   997 LFLEMFCMDPFVLVNRARP---PSTTTGQPHLYL----------------PDISEGKEVMPVPCV 1042

  Fly  1309 PISMDEQLAELANIEAINEQF-LRSEGLNTFQLLKENFYRCARQVSQENAEMQCDC--------- 1363
            . .:|..||  .|:....::. .|...:||                ..:..:.|||
Zfish  1043 N-EVDNTLA--PNVTYTKDRVPARGVFINT----------------SSDFMVGCDCTDGCRDRSK 1088

  Fly  1364 ------------FLTGDEEAQGHLSCGAGCINRML-------MIECGPLCSNGAR-CTNKRFQQH 1408
                        ..||     |.:...||..::.|       :.||.|||....| |:|:..|..
Zfish  1089 CACHKLTIEATSLCTG-----GPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHG 1148

  Fly  1409 QCWPCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFER--------------------- 1452
            ......:|.|:.||.||..:..:|.|.|:..:.|::::.::...
Zfish  1149 MQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEK 1213

  Fly  1453 -------------------------------RQHLYSKD-------------------------- 1460
                                           :..||.:|
Zfish  1214 LKEGYESEAYCSDTEVESSKKTITMKTGPLLKNSLYKEDSSSGEEPMEVDTAKDKVKVHDKPLGE 1278

  Fly  1461 -------------------------------------------------------------RNRH 1464
                                                                         :|..
Zfish  1279 RKLPNKPHETPKDTQKKISELRKNDGQESSGPKRCFAIKSFQRRVKPLESTEAQKEKTKTPKNTR 1343

  Fly  1465 YYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVN-GELR---IGFFSVKPIQPGEEITF 1525
            ..|.......:|||..:||:.|||||||.||...|...|: .:||   :.||:.|.|:.|.|:|:
Zfish  1344 GLFNDEDACYIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTW 1408

  Fly  1526 DYQYLRYGRDAQR---CYCEAANCRG 1548
            ||.| ..|....:   |.|.:..|.|
Zfish  1409 DYNY-EVGSVEGKVLLCCCGSLRCTG 1433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.